DSIP 99%+ High Purity Multiple Sizes:DS2/ DS5/DS10 per Vial buy - image1

  Product Detail  

Product Description – The Science of DSIP in Topical Skin Care

Delta Sleep Inducing Peptide (DSIP) is a naturally occurring nonapeptide first isolated in 1977 from the cerebral venous blood of rabbits during electrically induced sleep. Structurally, DSIP consists of nine amino acids with the sequence Trp‑Ala‑Gly‑Gly‑Asp‑Ala‑Ser‑Gly‑Glu and a molecular weight of 848.81 g/mol. Beyond its well‑studied neurological functions, DSIP has demonstrated significant antioxidant, anti‑inflammatory, and cytoprotective properties that make it a highly valuable ingredient for advanced cosmetic and skin care research.

Key Mechanisms for Skin Health

Potent Antioxidant Defense – Research has demonstrated that DSIP and its analogues exhibit considerable direct antioxidative activity, comparable to that of vitamin C and β‑carotene. In cell and tissue studies, DSIP suppresses lipid peroxidation and prevents the accumulation of malondialdehyde, a marker of oxidative damage. Topically, this translates into protection of collagen and elastin from free‑radical degradation, reducing visible signs of premature aging.

Strengthening the Skin‘s Antioxidant Barrier – DSIP exerts a stimulating influence upon key enzymatic antioxidants, including superoxide dismutase (SOD), catalase, and ceruloplasmin, as well as non‑enzymatic antioxidants such as urea and uric acid. By enhancing the skin’s own endogenous antioxidant defense system, DSIP helps fortify the skin‘s resilience against environmental aggressors.

Calming Inflammation & Stress Responses – DSIP has been shown to suppress excessive activation of stress‑activated protein kinases (SAPKs) such as c‑Jun N‑terminal kinase (JNK) and p38 MAPK, which are involved in inflammation and cellular stress responses. This mechanism may contribute to reduced redness, irritation, and sensitivity when incorporated into topical formulations.

Support for Skin Barrier & Recovery – Through its modulation of stress pathways, DSIP may help the skin better cope with circadian disruptions, UV exposure, and pollution. Research suggests that DSIP can influence various stress‑related processes, including regulation of corticosterone levels and adrenal responses. This positions DSIP as a candidate for “recovery” formulations designed to restore skin vitality after environmental or lifestyle stress.

Formulation Research Areas

DSIP is being explored in advanced skin care for:

• Anti‑aging serums – targeting oxidative stress and supporting collagen integrity

• Stress‑recovery creams – for skin exposed to pollution, lack of sleep, or daily urban stress

• Calming & redness‑reducing formulas – for sensitive, reactive, or post‑procedure skin

• Brightening & even‑tone products – by supporting healthy cell turnover and reducing oxidative pigmentation

1. Ultra-High Purity
Each batch is synthesized and purified to >99% purity (HPLC), ensuring reliable and reproducible results in sensitive experiments.
2.Accurate Dosing & Consistency
Our peptides are precisely weighed and vacuum-sealed under sterile conditions. Batch-to-batch consistency is rigorously maintained.
3.Endotoxin-Free & Sterile Processing
Manufactured in a cleanroom environment, our peptides are free from endotoxins, microbial contamination, and other impurities that could interfere with cell-based or in vivo studies.

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  We are a high-tech enterprise focusing on the research, development and production of peptide products. The company was established in recent years and is committed to applying advanced biotechnology to the health industry to meet the market's demand for high-quality, high-efficiency peptide products.
    As a leading peptide manufacturer,We have a R&D team composed of senior scientists and engineers, which continues to explore and innovate, and is committed to developing safer, more effective, and more market-competitive peptide products. The company's main products cover but are not limited to pharmaceutical grade, food grade and cosmetic grade and other fields, and are widely used in many aspects such as health care, disease prevention, beauty and skin care.
    In terms of production technology, We adopt internationally advanced production equipment and technology to ensure that every aspect of the product, from raw material selection, production and processing to finished product packaging, strictly follows relevant national standards and specifications to ensure product quality and safety. At the same time, the company has also established a complete quality management system and after-sales service system to provide customers with all-round, one-stop service support.
    Our company adhere to the corporate philosophy of "technology leads health, quality creates the future" and always adheres to the development path of people-oriented and technological innovation. The company not only focuses on product quality and innovation, but also actively fulfills its social responsibilities and is committed to promoting the development and progress of the health industry.
    In the future,We will continue to delve into the field of peptide product research and development, continue to explore and make breakthroughs, and strive to become a leader in the global peptide industry and make greater contributions to human health.