High Quality methyl 1H-indazole-3-carboxylate CAS 43120-28-1 Powder Fast Shipping Good Price

methyl 1H-indazole-3-carboxylate More Info

    Introduction

Pharmacological Profile

SLU‑PP‑915 is a potent pan‑ERR (Estrogen‑Related Receptor) agonist. It can activate all three ERR isoforms: ERRα, ERRβ and ERRγ, with EC ₅₀ values around 400 nM for each subtype.

It activates ERR‑mediated signaling pathways, which regulate mitochondrial biogenesis, oxidative phosphorylation, fatty‑acid oxidation and energy metabolism. Pre‑clinical studies indicate potential research value in mitochondrial function and metabolic disorders, cardioprotection against heart failure, as well as skeletal muscle remodeling and exercise‑mimetic metabolic adaptation.

Compared with SLU‑PP‑332, SLU‑PP‑915 shows oral bioavailability in animal models, which is its major advantage.

Application

This compound is intended for scientific research purposes only. It is a useful tool compound for studies on ERR‑related signaling, mitochondrial biology, metabolic disease and exercise physiology. It isnot approved for human use, and not for drug, food or cosmetic applications .

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Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

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Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

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Suitable for more than 50kg 
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We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

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2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders:
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.