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Home > Biochemical Engineering > Polypeptide > Retatrutide for Sale > Retatrutide Synthetic Peptide White Lyophilized Powder High Purity Biochemical Raw Material For In Vitro Laboratory Research
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Retatrutide Synthetic Peptide White Lyophilized Powder High Purity Biochemical Raw Material For In Vitro Laboratory Research

TDS 7459 Inquiries

Unit Price:

$20-21/BOU FOB

Get Latest Price
CAS No.:

2381089-83-2

Grade:

Research Grade

Content:

99%

Port:

guangdong

Brand:

OEM

Packaging:

5mg/10vials 10mg/10vials 20mg/10vials

Price valid (until):

2026-11-21

Company Type:
Trader
Location:
Hongkong, China
Qualification:
Main Products:

Tirzepatide,Retatrutide,Semaglutide,GHK-Cu

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Retatrutide is sealed in clean glass vials under low humidity environment to prevent moisture absorption. Shockproof outer packaging is adopted for international delivery. Cold insulating materials will be equipped when necessary to maintain sample stability. After receiving the parcel, please transfer the product to the specified low-temperature storage environment as soon as possible. When opening the vial, complete weighing and aliquoting quickly in dry surroundings. It is highly recommended to divide the powder into small tubes for separate preservation, which helps avoid repeated freeze-thaw cycles that accelerate peptide degradation.

    FOR IN-VITRO LABORATORY RESEARCH USE ONLY. This biochemical reagent is NOT intended for human ingestion, injection, medical diagnosis, disease treatment, cosmetic formulation, veterinary administration or any other unauthorized application. Any usage beyond academic laboratory research is strictly prohibited.

    Items Specifications
    Product Name Retatrutide
    Product Type Synthetic peptide
    CAS No. 2381089-83-2
    Purity HPLC ≥98%
    Identification Confirmed by Mass Spectrometry (MS)
    Appearance White lyophilized powder
    Synthesis Method Fmoc Solid Phase Peptide Synthesis
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      Product Detail  


    Retatrutide is a long-chain synthetic peptide produced by mature Fmoc solid-phase peptide synthesis technology. Sequential amino acid coupling is adopted in the synthesis workflow. Every coupling cycle is precisely monitored and controlled to minimize deletion fragments, truncated by-products and side-chain modification impurities. After cleavage from the solid resin carrier, the crude peptide undergoes multi-stage gradient reversed-phase chromatographic purification, desalting, ultrafiltration and concentration. The purified peptide solution passes through a 0.22 μm sterile membrane filter before vacuum freeze-drying treatment.

    The finished product appears as uniform white lyophilized powder. Vacuum freeze-drying removes most free water within the peptide sample, effectively inhibiting hydrolysis and oxidative degradation of peptide chains. This process greatly improves chemical stability during cross-border logistics and long-term cold storage. This product is a biochemical research reagent and is only suitable for in-vitro academic laboratory exploration. It can be used for a variety of non-clinical research directions, including peptide sequence and conformational characterization, molecular binding affinity screening, receptor interaction testing, in-vitro cell model experiments, biochemical signaling pathway research, peptide solubility and stability evaluation, and synthesis process optimization. It is widely used for exploratory experiments in university laboratories, scientific research institutes and biotechnology R&D teams.

    We maintain a comprehensive full-chain quality control system. Inspection links cover incoming raw amino acid verification, in-process sampling monitoring during synthesis, finished product comprehensive testing and packaging re-inspection. Each batch of finished products is tested by RP-HPLC for purity, and mass spectrometry (MS) is used to confirm the molecular identity and molecular weight of Retatrutide. Supplementary test indicators include appearance inspection, solubility test, residual moisture and impurity profile analysis. Batch-specific COA certificate with all test data can be provided upon request.

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      Why Choose Us 


    1. Mature Fmoc solid-phase synthesis process: stable coupling efficiency, low impurity background and consistent batch quality
    2. Multi-step gradient chromatographic purification: efficiently separate structurally similar peptide impurities to guarantee HPLC purity ≥98%
    3. Optimized freeze-drying technology: loose powder texture, excellent re-dissolving performance in matched aqueous buffer systems, no obvious agglomeration
    4. Flexible packaging options: standard vial specifications for laboratory use available, customized aliquot packaging service supported for research orders
    5. Complete supporting documents: COA, HPLC chromatogram, MS spectrum and MSDS safety data sheet can be supplied as required
    6. Reliable supply capacity: reasonable production scheduling, sufficient inventory and timely packing and shipment for global research customers
    7. Professional technical support: our peptide R&D team can share practical guidance on sample dissolution, aliquot operation and cold storage precautions
    Shop Retatrutide Synthetic Peptide White Lyophilized Powder High Purity Biochemical Raw Material For In Vitro Laboratory Research-Detailed Image 13
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      FAQ  



    Q1: What test documents can you provide for each batch? A: We can provide batch-specific COA, HPLC chromatogram and MS spectrum. MSDS is also available on request.

    Q2: How should I store Retatrutide after receiving it? A: Keep it sealed at -20℃ in a dry and dark environment. Avoid high temperature, high humidity and repeated freeze-thaw cycles.

    Q3: Can I get custom packaging size for my experiment? A: Yes, customized vial packaging is available for laboratory research orders, you can tell us your requirement.

    Q4: What solvent can be used to dissolve this peptide powder? A: It can be dissolved in buffer solutions selected according to your experimental scheme. It is recommended to prepare fresh stock solution before experiment.

    Q5: Do you accept small trial research orders? A: Sure, we support small-volume trial orders for laboratory study with flexible packing choices.

    ECHEMI Editorial Reference
    Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
    Retatrutide (LY-3437943) was discovered by the American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors) for obesity. The 2024 Lasker~DeBakey Clinical Medical Research Award has been given to Joel Habener and Svetlana Mojsov for their discovery of a new hormone GLP-1(7-37) and to Lotte Knudsen for her role in developing sustained acting versions of this hormone as a treatment for obesity.

    Certificates

    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

    CAS No.:

    2381089-83-2

    InChIKeys:

    MLOLQJNKXBNWFW-SAGGEDDASA-N

    Molecular Weight:

    0

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Categories:

    Polypeptide

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

    Research
    Class:

    Triple agonist — GCGR, GIPR, GLP-1R

    Status:

    Investigational (Phase 3)

    Mechanism:

    Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

    EC50 (Human GCGR):

    5.79 nM

    EC50 (Mouse GIPR):

    0.191 nM

    EC50 (Mouse GLP1R):

    0.794 nM

    EC50 (Mouse GCGR):

    2.32 nM

    EC50 (Human GLP1R):

    0.775 nM

    EC50 (Human GIPR):

    0.0643 nM

    Source:

    Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

    Clinical Development:

    NCT04881760; NCT05882045; NCT06354660

    References
    ChEMBL:

    CHEMBL5095485

    DrugBank:

    DB18993

    KEGG DRUG:

    D12430

    PubChem:

    PubChem

    Disclaimer:

    Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Tirzepatide,Retatrutide,Semaglutide,GHK-Cu

    Location:

    RM 701, UNIT 108, 7/F, TWR B NEW MANDARIN PLAZA 14 SCIENCE MUSEUM RD TSIM SHA TSUI HONG KONG

    Year of Establishment:

    2026

  • Inquiry History
    7459 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Retatrutide 2381089-83-2

    3 MT Mar 28, 2026
    United Kingdom

    Retatrutide - 2381089-83-2

    1 G Feb 10, 2026
    United States

    Retatrutide CAS 2381089-83-2 10mg vial

    20 MT Mar 7, 2026
    United States

    Factory Retatrutide API 99% Purity CAS 2381089-83-2

    5 KG Nov 10, 2025
    United Kingdom

    Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA

    1 MT Mar 22, 2026
    United States

    2381089-83-2

    100 G Jul 14, 2026
    United States

    2381089-83-2

    100 G Feb 24, 2026
    United States

    2381089-83-2

    100 MT Dec 9, 2023
    United States

    Retatrutide 2381089-83-2

    200 MG May 16, 2026
    United Kingdom

    2381089-83-2 retatrutide

    300 MG Feb 13, 2026
    United States

    Retatrutide 2381089-83-2 wholesale

    500 MT Nov 3, 2023
    United States

    Retatrutide CAS 2381089-83-2 99%

    10 PCS Feb 21, 2026
    Poland

    CAS 2381089-83-2 (Custom Peptide)

    40 MT Apr 10, 2026
    Austria

    Peptide Retatruide CAS 2381089-83-2

    100 MT Apr 4, 2026
    Austria

    Retatrutide CAS 2381089-83-2 10mg vial

    20 PCS Feb 10, 2026
    United States

    GLP-1 / GIP Retatrutide cas 2381089-83-2

    1 MT Oct 16, 2024
    United States

    Retatrutide 99% High Quality CAS 2381089-83-2

    1 G Jan 23, 2026
    Australia

    GMP Grade 99% Retatrutide Lyophilized Powder CAS 2381089-83-2

    10 G Jun 12, 2026
    Palestine

    Factory 99% Purity Retatrutide Peptide CAS 2381089-83-2 Door-To-Door Service

    10 MG Mar 16, 2026
    United States

    Factory 99% Purity Retatrutide Peptide CAS 2381089-83-2 Door-To-Door Service

    20 MG Feb 4, 2026
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