99% High Purity Mazdutide raw materials GLP-1 Weight Loss Peptides Cas 2259884-03-0 factory sellingReady stock

Name:Helen
Whatsapp:+86 15731953230
                            Email ：dx15731953230@163.com                                                                                                                                        sincerely look forward to your inquiries about our products.                                  

Mazdutide  is a global first and the first to be approved for market use, a dual receptor for glucagon (GCG) and glucagon-like peptide-1 (GLP-1), belonging to a long-acting synthetic gastrin-releasing peptide (OXM) analog.
Core efficacy
   1. Significant weight loss effect
In overweight/obese adults, a 6 mg dose treatment for 48 weeks resulted in an average weight loss of 14.01%, and some patients achieved a maximum reduction of 21% (high dose 16 mg, in clinical trial stage)
The proportion of patients with weight loss ≥ 5%: 82.8% in the 6 mg group (vs 11.5% in placebo)
The average reduction in waist circumference: 10.96 cm (6 mg group)
   2. Improved blood glucose control (applicable to type 2 diabetes)
After 24 weeks of treatment, glycated hemoglobin (HbA1c) decreased by 2.15% (6 mg group), superior to placebo (-0.14%) and dulaglutide
In patients with type 2 diabetes combined with obesity, 48% of patients achieved the dual goals of HbA1c < 7.0% and weight loss ≥ 10%, significantly better than semaglutide (21%)
   3. Improved liver fat metabolism
For patients with baseline liver fat content ≥ 10%, liver fat content decreased by 80.2% after 48 weeks of treatment
Significantly increased the proportion of liver fat returning to normal (< 5%)
Multiple metabolic benefits
Blood pressure: Systolic blood pressure decreased by approximately 6.75 mmHg
Blood lipids: Triglycerides ↓ 0.52 mmol/L, total cholesterol ↓ 0.45 mmol/L, LDL-C ↓ 0.31 mmol/L

Q: Are you a supplier or manufacturer?
A: We are both a supplier and a manufacturer.
Q: How do you ship?
A: We have established good partnerships with DHL, TNT, UPS, FEDEX, EMS, and China Air Post. For containerized products, we offer ocean shipping. You can also choose your own freight forwarder.
Q: What payment methods do you accept?
A: Bitcoin, PayPal, USDT.
Q: What is the after-sales service like?
A: We provide high-quality products and ensure 100% safe delivery.
Q5: How do we guarantee quality?
A: We will first send you a Certificate of Analysis (COA) so you can confirm the quality.
Q6: How can I confirm product quality before placing an order?
A: Free samples are available for some products. You only need to pay the shipping fee or arrange for a courier to come and collect the sample. You can send us your product specifications and requirements, and we will produce according to your requirements.
Q7: Are there discounts?
A: Yes, we always offer better prices for large orders.

Hangzhou Yueshou Trading Co., Ltd. At the core of our operations is the unwavering commitment to our guiding principles : "Quality First, Service Supreme."Our mission is to spearhead advancements in biotechnology by consistently upholding the highest standards of quality and service. Through innovation and excellence, we aim to contribute to the betterment of global health and well-being.
   Our primary focus encompasses a range of products , including weight loss peptideses, cosmetic peptides, and customized peptides. Notable among our weight loss peptide offerings are Tirzepatide, Retatrutide, and others.Provides reliable and timely custom manufacturing services for API following stringent quality system and close communication with the Clients.We have professional sales team , focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market, our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.
   With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

ECHEMI Editorial Reference
Mazdutide is a peptide-based GLP-1 and glucagon receptor (GCGR) dual agonist. As a pharmaceutical raw material, Mazdutide is characterized by its dual receptor activity and defined peptide structure. It is suitable for API research, analytical testing, pharmaceutical development, and related manufacturing processes.

Certificates

Basic Info
Product Name:Mazdutide
Other Name:Mazdutide;Mazdutide acetate;Mazdutide 10mg;Mazdutide 5mg 10mg;LY-3305677;Mazdutide (IBI-362;OXM-3)Mazdutide;Mazdutide acetate;Mazdutide 10…
CAS No.:2259884-03-0
Molecular Weight:0
EC Number:884-103-0
Color/Form:White to off-white
Categories:Other Chemical Drugs

Research
Class:Dual GLP-1R/GCGR agonist (long-acting peptide)Dual GLP-1R/GCGR agonist (long-acting pep…
Status:Investigational — Phase 3 (China)
Mechanism:A long-acting dual agonist of the GLP-1 receptor (GLP-1R, Ki = 28.6 nM) and glucagon receptor (GCGR, Ki = 17.7 nM). The dual activation provides both glycemic control (via GLP-1R) and increased energy expenditure / hepatic lipolysis (via GCGR), producing weight loss beyond what GLP-1R agonism alone achieves.A long-acting dual agonist of the GLP-1 rece…
EC50 (GLP1R Ki):28.6 nM
EC50 (GCGR Ki):17.7 nM
Source:GlpBio: Mazdutide (CAS 2259884-03-0); Innovent Phase Ib results (eClinicalMedicine 2022).GlpBio: Mazdutide (CAS 2259884-03-0); Inno…DOI
Clinical Development:NCT04930343; NCT05592656

References
PubChem:PubChem
Literature:GlpBio: Mazdutide (CAS 2259884-03-0); eClinicalMedicine: Innovent Phase Ib results (2022); ClinicalTrials.gov: DREAMS-1 (NCT04930343)
Disclaimer:Mazdutide is NOT FDA-approved or EMA-approved. It is in Phase 3 clinical trials in China. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.