NACA N-Acetylcysteine Amide
5 Inquiries
38520-57-9
99%
Shanghai
1KG foil bag
Yes
2026-11-23
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Product Details
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Seller Information
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Inquiry History
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Description# N-Acetylcysteine Amide (NACA) Product Introduction
**Synonym**: NACA**CAS No.**: 38520-57-9**Molecular Formula**: C₅H₁₀N₂O₂S**Molecular Weight**: 162.21**Purity**: ≥98% (HPLC)**Appearance**: White crystalline powder
N-Acetylcysteine Amide (NACA) is a lipophilic thiol antioxidant, the amide derivative of N‑acetylcysteine (NAC). Compared with NAC, the amide modification greatly improves lipophilicity, cell membrane permeability and blood‑brain barrier penetration, enabling better intracellular uptake and higher bioavailability.
NACA acts as a precursor of glutathione (GSH). It effectively scavenges reactive oxygen species (ROS), restores intracellular GSH levels, relieves oxidative stress, reduces lipid peroxidation and protects mitochondrial function. It also exhibits anti‑inflammatory and neuroprotective effects in multiple preclinical modelsPMC.
This product is widely used for scientific research, including neuroprotection, brain injury, retinal disease, liver toxicity, mitochondrial function and redox biology studies. It is also available as a raw material intermediate for cosmetic and pre‑formulation development. Strict HPLC testing is adopted to guarantee stable batch quality.
## Key Features
- Superior cell & blood-brain barrier permeability vs NAC- Efficient GSH replenishment and ROS scavenging activity- Neuroprotective and anti‑oxidative properties- High purity ≥98%, stable quality with COA- Good solubility in DMSO, ethanol and aqueous buffer- Traceable batch QC support
## Typical Research Applications
- Oxidative stress & glutathione metabolism research- Neuroprotection, traumatic brain injury, spinal cord injury- Retinal degeneration and ophthalmic preclinical study- Hepatic toxicity, mitochondrial function research- Antioxidant raw material for cosmetic & formulation screening
## Storage & Handling
- Storage: Sealed at -20°C, protect from light and moisture- Long shelf life under recommended storage condition- Shipping: Room temperature for short transport
**Disclaimer**: For research use only. Not for human clinical, diagnostic or direct food use.
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### Short Version (for Alibaba / product catalogue)
**N-Acetylcysteine Amide (NACA)**CAS: 38520-57-9, Purity ≥98% HPLCNACA is a lipophilic thiol antioxidant derived from NAC. It features enhanced cell and blood-brain barrier permeability, replenishes intracellular GSH, scavenges ROS and delivers neuroprotective effects. Widely applied in oxidative stress, neuroscience, ophthalmology and mitochondrial research. White powder, full QC documentation available. For research use only.Basic Info-
Product Name:
N-Acetylcysteine amide
Other Name:Propanamide,2-(acetylamino)-3-mercapto-,(2R)-;Propanamide,2-(acetylamino)-3-mercapto-,(R)-;(2R)-2-(Acetylamino)-3-mercaptopropanamide;N-Acetyl-L-cysteinamide;N-Acetylcysteine amide;(2R)-2-Acetamido-3-sulfanylpropanamide;(R)-2-Acetamido-3-mercaptopropanamide
CAS No.:38520-57-9
Molecular Formula:C5H10N2O2S
InChIKeys:InChIKey=UJCHIZDEQZMODR-BYPYZUCNSA-N
Molecular Weight:282.33716
Exact Mass:162.21
Categories:
Characteristics-
PSA:
73.2
XLogP3:-0.3
Appearance:white to off-white
Density:1.226±0.06 g/cm3(Predicted)
Melting Point:147-149 °C @ Solvent: Ethanol
Water Solubility:H2O: ≥20mg/mL
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
500
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Location:
NO.2 High Tech Road ,Xi'an,China
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Year of Establishment:
2025
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Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted 
Israel
N-Acetylcysteine amide,
1 KG Mar 23, 2025 
United Kingdom
Nac amide
10 G Feb 28, 2025 
India
N-Acetyl L-Cystine
25.00 KG Jul 17, 2024 
Thailand
N-Acetylcysteine amide
1 KG Jun 13, 2024
Israel
N-acetylcysteine amide
1 KG Nov 1, 2023 Post an enquiry for this product
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