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Home > Chemical Reagents > Organic Reagents > Vorinostat for Sale > Vorinostat (CAS 149647-78-9) Manufactured by Shaanxi Dideu Medichem Co., Ltd.99%
Vorinostat (CAS 149647-78-9) Manufactured by Shaanxi Dideu Medichem Co., Ltd.99% buy - large image1
Vorinostat (CAS 149647-78-9) Manufactured by Shaanxi Dideu Medichem Co., Ltd.99% buy - image1
Vorinostat (CAS 149647-78-9) Manufactured by Shaanxi Dideu Medichem Co., Ltd.99% buy - image2
Vorinostat (CAS 149647-78-9) Manufactured by Shaanxi Dideu Medichem Co., Ltd.99% buy - image3
Vorinostat (CAS 149647-78-9) Manufactured by Shaanxi Dideu Medichem Co., Ltd.99% buy - image4
Vorinostat (CAS 149647-78-9) Manufactured by Shaanxi Dideu Medichem Co., Ltd.99% buy - image5
Vorinostat (CAS 149647-78-9) Manufactured by Shaanxi Dideu Medichem Co., Ltd.99% buy - image6

Vorinostat (CAS 149647-78-9) Manufactured by Shaanxi Dideu Medichem Co., Ltd.99%

TDS 16 Inquiries

Unit Price:

$1/G FOB

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CAS No.:

149647-78-9

Grade:

Industrial Grade

Content:

99%

Port:

xi'an

Brand:

Dideu

Packaging:

1g/Bag

Sample Available:

Yes

Price valid (until):

2026-11-29

Company Type:
Manufactory
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    • Appearance: White to off-white crystalline powder.
      Melting point: 161 – 162 °C
      Storage conditions: Powder should be stored dry and protected from light at -20°C; DMSO stock solutions should be aliquoted and stored at -80°C.

    • Chemical and biochemical research and development, and other cutting-edge research.

    Shop 2800223-30-5,TYRA-300-Detailed Image 1


    Our Reference Specification, for more details, pls contact us for COA,MSDS and certification:
    Email & Skype: 1082@dideu.com Telephone:+86-17392703752
    Mobile&Wechat&Whatsapp: +8617392703752





    Shop 2800223-30-5,TYRA-300-Detailed Image 2


    Items Standard
    Test Results

    Identification

    A.H-NMR:Comply with the structure
    Complies
    B.LC-MS:Comply with the structure
    Complies
    C.The IR spectrum of sample should be identical with that of reference standard.
    Complies
    D.HPLC-ESI-MS
    The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.



    Complies
    Loss on drying % ≤2.0
    0.19
    Heavy metals ppm ≤10 
    <10
    Moisture % ≤1.0
    0.1
    Sulphated ash % ≤0.5 determined on 1.0 g.
    0.009
    Residue on ignition % ≤0.1
    0.03

    Related Substances %

    Unspecified impurities: for each impurity ≤0.10 <0.10
    Total Impurity ≤0.5 0.18
    Purity % ≥99.0
    99.7
    Assay % 99.0 ~101.0 (anhydrous substance).
    99.8
    Storage Preserve in well-closed, light-resistant and airtight containers.
    Complies

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    Our normal packaging is 25kgs/Drum,200kgs/Drum
    The packaging can be customized. the shipping term can be by sea, by air, and sample or small quantity can be shipped by DHL, FEDEX, EMS and TNT.


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    Shop 2800223-30-5,TYRA-300-Detailed Image 9


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    a) Free sample can be supplied.
    b) Guide our clients by professional knowledge and teach them how to use our product after sales.
    c) Accept SGS,BV any other third-party inspection before loading.
    d) High quality best price Guaranteed.

    Shop 2800223-30-5,TYRA-300-Detailed Image 11


    Why do you choose Dideu Industries as your partner?


    A) High quality can be guaranteed. Dideu Industries since 1975 are reputed chemical manufacturer and are Certified by ISO 9001;2015 and have GMP certification.Free sample can be arranged before shipment and SGS,BV and other third party inspection company are accepted before loading.For regular customers, we accept L/C 180 Days, D/P,D/A payment term. If there is any quality problem after goods arrive. Dideu Industries will do fully payment refund.


    B) Best price can be guaranteed. As Dideu Industries are integrated pharmaceuticals and chemicals producer, the production cost can be controlled and price will be definitely more competitive than China trading companies.


    C) Professional enginners from Dideu Industries will give professional usage guide and services after sales.


    D)Dideu Industries work 7×24 hours and your request will be processed by our professional staff in different shift period.


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    Shop 2800223-30-5,TYRA-300,Dabogratinib,Shaanxi Dideu,gold product.Manufacturer, Discount-Detailed Image 13


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    Dideu Industries is one of the largest producer for general chemical, pharmaceutical, nutrition additive, natural extracts, agrochemical and Daily-Use Chemical in China and is headquartered in Shaanxi, China. The Dideu Group comprises subsidiaries and joint ventures in more than 10 countries and operates six integrated production sites and 21 other production sites in Europe, Asia, Australia, Americas and Africa.Its headquarters is located in Xi’An,China. Dideu has customers in over 200 countries and supplies products to a wide variety of industries.


    At the end of 2014, the company employed more than 13000 people. In 2014, Group Dideu posted sales of 30 billion and income from operations before special items of about 7.5 billion. The company is currently expanding its international activities with a particular focus on Asia countries. Between 1990 and 2005, the company invested 5.2 billion in Asia, for example in sites near Guangxi,Yunnan, Sichuan, Shaanxi China,Mangalore in India,Bangkok, Thailand,Hanoi, Vietnam etc.


    Dideu Industries Consist Of Five Industry Chains:

    I)Pharmaceutical Industries
    II)Nutrition Additive Industries
    III)Daily-Use Chemical Products Industries & Agrochemicals
    IV)Environmental Friendly Chemical And Chemurgy Industries
    V)Petrochemical Industries
    VI)General Chemical Industry


    At Dideu, we redefine chemistry to make the world better - and have been doing so for 75 years. As one of the world's leading chemical company, we combine economic success with environmental protection and social responsibility.Through science and innovation we enable our customers in nearly every industry to meet the current and future needs of society.


    At Dideu, we create chemistry for a sustainable future with science for a better life.Dideu is a Life Science company with a long and glorious history and core competencies in the areas of health care and agriculture. With our innovative products, we are contributing to finding solutions to some of the major challenges of our time. The growing and increasingly aging world population requires improved medical care and an adequate supply of food. Dideu is improving people's quality of life by preventing, alleviating and treating diseases. And we are helping to provide a reliable supply of high quality food, feed and plant based raw materials.We develop new molecules for use in innovative products and solutions to improve health. Our research and development activities are based on a profound understanding of the biochemical processes in living organisms.Our goal is to achieve and sustain leadership positions in our markets, thus creating value for our customers, stockholders and employees. To this end, our strategy is designed to help solve some of the most pressing challenges facing humankind, and by doing this exceptionally well we aim to strengthen the company's earning power.


    We are committed to operating sustainably and addressing our social and ethical responsibilities as a corporate citizen, while at the same time respecting the interests of all our stakeholders. Employees with a passion for innovation enjoy excellent development opportunities at Dideu.Exclusive Focus on the Life Science BusinessesFollowing the economic and legal independence of our former Material Science subgroup.Dideu has charted the course for its successful development as a Life Science company. Our Life Science businesses hold leading positions in innovation driven growth markets. Together they make up a strong, attractive and balanced portfolio that is resistant to fluctuations in demand and to potential risks.The previous structure comprising a strategic management holding company and operational subgroups has thus been replaced by an integrated organization under the umbrella of the strong Dideu brand. The company's operations are managed in three divisions Pharmaceuticals, Consumer Health and Crop Science and the Animal Health business unit.The business continues to be supported by the corporate functions, Dideu Business Services and the service company Currenta, while Technology Services is being integrated into Dideu Group, forming the Engineering and Technology function.


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    Items Specifications
    purity 99




    ECHEMI Editorial Reference
    It is the first HDAC inhibitor approved by the US Food and Drug Administration (FDA) for the treatment of cutaneous T-cell lymphoma (CTCL) with significant skin involvement that is still progressing, resistant or relapsing after two systemic regimens. On October 6, 2006, the US Food and Drug Administration (FDA) have approved vorinostat capsules (vorinostat) for the treatment of skin cancer drugs. The drug is the first novel type of anti-cancer drugs of histone deacetylase inhibitor devel.
    Solid
    Vorinostat is a dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL). It has a role as an EC 3.5.1.98 (histone deacetylase) inhibitor, an apoptosis inducer and an antineoplastic agent. It is a hydroxamic acid and a dicarboxylic acid diamide. It derives from a suberic acid, a hydroxylamine and an aniline.|Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes back during or after treatment with other medicines. It is the first in a new class of agents known as histone deacetylase inhibitors. A recent study suggested that vorinostat also possesses some activity against recurrent glioblastoma multiforme, resulting in a median overall survival of 5.7 months (compared to 4 - 4.4 months in earlier studies). Further brain tumor trials are planned using combinations of vorinostat with other drugs.|Vorinostat is a Histone Deacetylase Inhibitor. The mechanism of action of vorinostat is as a Histone Deacetylase Inhibitor.|Vorinostat is an oral histone deacetylase inhibitor and antineoplastic agent that is approved for use in refractory or relapsed cutaneous T cell lymphoma. Vorinostat is associated with modest rate of minor serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent liver injury.|Vorinostat is a synthetic hydroxamic acid derivative with antineoplastic activity. Vorinostat, a second generation polar-planar compound, binds to the catalytic domain of the histone deacetylases (HDACs). This allows the hydroxamic moiety to chelate zinc ion located in the catalytic pockets of HDAC, thereby inhibiting deacetylation and leading to an accumulation of both hyperacetylated histones and transcription factors. Hyperacetylation of histone proteins results in the upregulation of the cyclin-dependant kinase p21, followed by G1 arrest. Hyperacetylation of non-histone proteins such as tumor suppressor p53, alpha tubulin, and heat-shock protein 90 produces additional anti-proliferative effects. This agent also induces apoptosis and sensitizes tumor cells to cell death processes. Vorinostat crosses the blood-brain barrier.|A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.

    Certificates

    Basic Info
    Product Name:

    Vorinostat

    Other Name:

    Octanediamide,N1-hydroxy-N8-phenyl-;Octanediamide,N-hydroxy-N′-phenyl-;N1-Hydroxy-N8-phenyloctanediamide;SAHA;Suberoylanilide hydroxamic acid;Vorinostat;Zolinza;N-Hydroxy-N′-phenyloctanediamide;Suberoyl anilide bishydroxamide;WT 171

    CAS No.:

    149647-78-9

    Molecular Formula:

    C14H20N2O3

    InChIKeys:

    InChIKey=WAEXFXRVDQXREF-UHFFFAOYSA-N

    Molecular Weight:

    264.32

    Exact Mass:

    264.32

    EC Number:

    1308068-626-2

    UNII:

    58IFB293JI

    NSC Number:

    759852|748799|701852

    DSSTox ID:

    DTXSID6041133

    NCI Thesaurus Code:

    C1796

    Color/Form:

    White to light orange powder|White solid

    ATC Code:

    L - Antineoplastic and immunomodulating agents

    HScode:

    29280000

    Categories:

    Organic Reagents

    Characteristics
    PSA:

    78.4

    XLogP3:

    1.9

    Appearance:

    white to tan

    Density:

    1.2

    Melting Point:

    159-160.5 °C

    Refractive Index:

    1.567

    Water Solubility:

    DMSO: ≥15mg/mL

    Storage Conditions:

    -20°C Freezer

    Vapor Pressure:

    2.6X10-13 mm Hg at 25 deg C (est)

    PH:

    pH = 6.6 (saturated water solution)

    PKA:

    9.2None

    Henrys Law Constant:

    Henry's Law constant = 1.23X10-14 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    9.2|pKa = 9.2

    Experimental Properties:

    ... no chiral centers and is non-hygroscopic|Hydroxyl radical reaction rate constant = 3.147X10-11 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Germ cell mutagenicity, Category 2

    Reproductive toxicity, Category 1A

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H341 Suspected of causing genetic defects

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

    Location:

    https://www.dideu.com/en/

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2016

    Company Certificates
    • Shaanxi Dideu Medichem Co. LtdISO Certificate ISO Certificate
    • Shaanxi Dideu Medichem Co. LtdREACH REACH
    Company Profile
    ">Company Profile
  • Inquiry History
    16 Inquiries
    Country Product Purchase Quantity Date Posted
    Denmark

    Vorinostat

    5 G Oct 29, 2026
    United States

    Vorinostat

    1 G Sep 28, 2026
    Spain

    Vorinostat

    10 G Aug 20, 2026
    Australia

    Vorinostat

    10 G Aug 9, 2026
    Italy

    Vorinostat

    10 G Aug 5, 2026
    Belgium

    vorinostat

    2 G Apr 16, 2026
    Jordan

    Vorinostat

    1000 MG Jan 30, 2026
    United States

    Vorinostat

    3 G Aug 6, 2025
    Saudi Arabia

    Vorinostat

    5 KG Jul 6, 2025
    United States

    Vorinostat

    50 G Jul 6, 2025
    United Kingdom

    Vorinostat

    5 G Jul 6, 2025
    United States

    Vorinostat

    2 KG Jun 28, 2025
    Austria

    Vorinostat

    2000 MG Jun 7, 2025
    Russia

    Vorinostat

    100 G Mar 3, 2025
    Brazil

    Vorinostat

    5  Feb 22, 2025
    Cyprus

    Vorinostat

    100 G Nov 26, 2024
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