High Purity CAS NO. 159635-49-1 tert-Butyl 4-methylenepiperidine-1-carboxylate Pharmaceutical Intermediate for Organic Synthesis
TDS
159635-49-1
Industrial Grade
99%
Qingdao
N/A
25KG/Drum
Yes
2026-10-26
Chemicals,Glabridin,Phenylethyl Resorcinol,Ascorbyl Tetraisopalmitate,Alpha-Arbutin,Kojic Dipalmitate
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Product Details
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Seller Information
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Description
Product Name tert-Butyl 4-methylenepiperidine-1-carboxylate CAS No. 159635-49-1 Appearance Colorless to Light Yellow or Light Orange Clear Liquid Molecular Formula C₁₁H₁₉NO₂ Molecular Weight 197.27 g/mol
Product Description
tert-Butyl 4-methylenepiperidine-1-carboxylate, also known as N-Boc-4-Methylenepiperidine, is a specialized nitrogen-containing organic compound with the CAS number 159635-49-1. It has a molecular formula of C₁₁H₁₉NO₂ and a molecular weight of approximately 197.27 g/mol. The compound features a piperidine ring protected by a tert-butoxycarbonyl (Boc) group and an exocyclic methylene group, making it a useful building block for organic synthesis and chemical intermediate development.
The combination of its protected nitrogen functionality and reactive carbon–carbon double bond provides opportunities for further structural modification in suitable synthetic routes. This compound may be considered for pharmaceutical intermediate research, heterocyclic compound synthesis, and fine chemical development. Its suitability depends on the intended target molecule, reaction conditions, and technical requirements of the customer.
Key Functions
Specialized building block for organic synthesis and intermediate development.
Boc-protected piperidine structure for selected synthetic routes.
Exocyclic methylene group for potential chemical transformations.
Potential starting material for the preparation of structurally diverse nitrogen-containing compounds.
Suitable for evaluation in pharmaceutical intermediate research and fine chemical synthesis.
Mechanism of Action
This compound is a chemical synthesis intermediate rather than a finished pharmaceutical ingredient. Its chemical reactivity is associated with the exocyclic carbon–carbon double bond and the Boc-protected piperidine nitrogen. The double bond may participate in suitable addition, reduction, or other functionalization reactions, depending on the reagents and reaction conditions.
The Boc group serves as a protecting group for the piperidine nitrogen during selected synthetic steps. Under appropriate conditions, it may be removed to provide access to the corresponding nitrogen-containing intermediate for further chemical modification. The actual reaction pathway and suitability depend on the target structure and the established synthetic process.
Advantages and Benefits
Clearly identifiable chemical structure and CAS number.
Specialized piperidine-based molecular framework.
Reactive methylene functionality for selected synthetic transformations.
Boc protection supports controlled nitrogen functionalization strategies.
Suitable for evaluation in organic synthesis and chemical intermediate development.
Supply and Customer Support
Product quality should be evaluated using the actual batch specifications and appropriate analytical documentation. Customers are encouraged to confirm the required assay, impurity profile, appearance, packaging, storage conditions, and other technical requirements before ordering. A Certificate of Analysis (COA), Safety Data Sheet (SDS), and Technical Data Sheet (TDS) may be provided subject to actual availability and the product grade supplied.
Shandong Keyang Materials Technology Co., Ltd. supplies specialty materials and chemical raw materials for international B2B customers. We aim to support customers with product information and supply solutions according to their technical and procurement requirements.
Please contact us to discuss product specifications, quality documentation, packaging details, supply availability, and a quotation. We welcome inquiries from pharmaceutical intermediate distributors, fine chemical traders, research organizations, and chemical manufacturers seeking a suitable supply partner for their business needs.
Please share your required purity, preferred grade, intended application, and target purchase quantity to help identify the appropriate product and prepare a quotation.Company ProfileShandong Keyang Materials Technology Co., Ltd. is a supplier of fine chemicals and cosmetic ingredients, specializing in vitamin derivatives and cosmetic active ingredients. Our product portfolio includes Ascorbyl Tetraisopalmitate (VC-IP) and other ingredients for personal care and skincare formulations.
We are committed to providing suitable ingredient solutions for cosmetic manufacturers, skincare brands, OEM/ODM companies, and ingredient distributors worldwide. We focus on product quality, reliable supply, competitive pricing, and responsive customer service to support our customers' sourcing needs.
We welcome inquiries from global partners seeking cosmetic raw materials and fine chemical ingredients. Product specifications, technical data sheets (TDS), safety data sheets (SDS), certificates of analysis (COA), and quotations can be provided upon request, subject to product availability.Certifications
Packing & Delivery
FAQ1.Are you a factory or trading companyWe are a company integrating manufacturer and trading company
2.How is the quality I want to test.Before production and extraction, we will test all raw materials.Quality is our top priority. All products are strictly tested and confirmed by our QC and QA, approved by Third Party Lab in China.So you will be assured with Good Quality if you choose us. We welcome you test the product and hope to get your feedback.
3.Can I get a Free sampleYes, For most products we can provide you a free sample. Plesae be free to consult our salesman.For a larger quantity, we always support you with better price.
4. What's your main payment methodT/T (Bank transfer), WU, MoneyGram, Wechat,Alipay,Credit card payment.
5.What modes of transportation do you have to chooseWe cooperate with HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post ,sea transportation etc.And with the SAFE SHIPPING in each country, you can receive the goods smoothly.It is fast and safe method.
6.How is the goods packedWe usually send goods with disguise package outside and a double-layer sterile transparent bag inside.We have tried thousand of package methods, it looks serious and discreet.
7.How to proceed orderAfter you confirm all details of order, pay money in advance and give us Shipping address.We arrange the shipment at first time after receive payment and offer after-sales service after you receive parcel.
8.When will I receive the shipping number Where I can check status of my orderAfter the goods are sent out, our staff will send you the shipping number via email, online or WhatsApp ASAP.You can also check the status online on 17track.
Research & Reference NoteHigh Purity CAS NO. 159635-49-1 tert-Butyl 4-methylenepiperidine-1-carboxylate Pharmaceutical Intermediate for Organic Synthesis is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Authoritative sourcesDisclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals
Certificates-
TDS
Basic Info-
Product Name:
1-Boc-4-methylenepiperidine
Other Name:TERT-BUTYL 4-METHYLENEPIPERIDINE-1-CARBOXYLATE;N-BOC-4-METHYLENEPIPERIDINE;1-N-BOC-4-METHYLENE-PIPERIDINE;4-METHYLENE-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;4-METHYLENEPIPERIDINE, N-BOC PROTECTED;1-Boc-4-Methylene-piperidine;4-Methylenepiperidine, N-BOC protected 97%;Boc-4-methylenepiperidine
CAS No.:159635-49-1
Molecular Formula:C11H19NO2
InChIKeys:PDTZMULNKGUIEJ-UHFFFAOYSA-N
Molecular Weight:197.27
Exact Mass:197.141586
EC Number:1312995-182-4
DSSTox ID:DTXSID90373553
HScode:2933399090
Categories:
Characteristics-
PSA:
29.5
XLogP3:1.9
Density:1g/ml
Boiling Point:80°C/1mmHg(lit.)
Flash Point:109.6±24.3 °C
Refractive Index:1.4630 to 1.4670
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Chemicals,Glabridin,Phenylethyl Resorcinol,Ascorbyl Tetraisopalmitate,Alpha-Arbutin,Kojic Dipalmitate
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Location:
Room 805, No. 178 Yingchun Street, Laishan District, Yantai City, Shandong Province
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
20 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
5-10
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Year of Establishment:
2026
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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