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SAG 21k, 3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(Methylamino)cyclohexyl)benzo[b]thiophene-2-carboxamide, CAS 946002-48-8

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Unit Price:

$180-220/KG FOB

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CAS No.:

946002-48-8

Grade:

Research Grade

Content:

98%

Port:

Shanghai

Packaging:

10mg/bottle

Price valid (until):

2026-12-05

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Chemfine International Co., Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

D/P,L/C,D/A,TT against B/L draft before shipment

Average Lead Time:

14 days

Qualification:

Main Products:

Organic Intermediate

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Description

SAG 21k CAS 946002-48-8 ≥98% HPLC Research Compound Hedgehog SMO Agonist

**SAG 21k**
CAS No.: 946002-48-8

Chemical Name: 3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(Methylamino)cyclohexyl)benzo[b]thiophene-2-carboxamide

**Description**

SAG 21k is a potent, orally active Smoothened (SMO) agonist of the Hedgehog signaling pathway. It can cross the blood-brain barrier and is widely used for life science research, developmental biology and tumor mechanism study.

**Specification**

Purity: ≥98% (HPLC)

Appearance: Off-white to pale yellow solid

Storage Condition: Store at -20°C, sealed, dry and protected from light.

**Documents**

COA (Certificate of Analysis), HPLC, NMR are available upon request.

Basic Info

Product Name:
3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide

Other Name:
SAG 21k;3-chloro-4,7-difluoro-N-[(2-methoxy-5-pyridin-4-ylphenyl)methyl]-N-[4-(methylamino)cyclohexyl]-1-benzothiophene-2-carboxamide;3-Chloro-4,7-difluoro-N-[[2-methoxy-5-(4-pyridinyl)phenyl]methyl]-N-trans-4-(methylamino)cyclohexyl]benzo[b]thiophene-2-carboxamide;3-chloro-4,7-difluoro-N-{[2-methoxy-5-(pyridin-4-yl)phenyl]methyl}-N-[trans-4-(methylamino)cyclohexyl]-1-benzothiophene-2-carboxamide;SCHEMBL12678477;SCHEMBL12678631;SCHEMBL12678943;SCHEMBL14202180;SCHEMBL20535825;AKOS030210943

CAS No.:
946002-48-8

Molecular Formula:
C29H28ClF2N3O2S

InChIKeys:
YVIFQUJDZSAFKG-UHFFFAOYSA-N

Molecular Weight:
556.0663264

Exact Mass:
555.156

EC Number:
-0

Categories:
Anticaking Agent

Characteristics

PSA:
82.7

XLogP3:
6.5

See More 3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide Properties 
Seller Information

Business Type:
Trader

Main Products:
Organic Intermediate

Location:
Room 1001, No. 3 Building, Jiaye International City, Jinrong 3 Street

Payment Terms:
D/P,L/C,D/A,TT against B/L draft before shipment

Average lead Time:
14 days

Total Annual Revenue:
$50 million-$100 million

Total Employees:
11-50

Year of Establishment:
2003

Over 20 Years Of Excellent

Manufacturing And First-Class Quality!

ChemFine International Co., Ltd. (CFI Chemical Supply), since 2003, has sprawled its network with offices and fostered deep collaborations with factories nationwide in China. Navigating the nuanced Chinese market, our focus remains on fulfilling customer expectations and ensuring optimal cost-performance. We eagerly welcome your visits to our partner factories. With a longstanding commitment, CFI, as a holistic chemical trading firm, specializes in sourcing fine chemicals globally.

Inquiry History

91 Inquiries

Country	Product	Purchase Quantity	Date Posted
Australia	SAG21K	50 MG	Nov 9, 2026
United States	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	300 MG	Nov 9, 2026
United States	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	500 MG	Nov 9, 2026
Russia	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	100 MG	Nov 7, 2026
Slovenia	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	100 MG	Nov 6, 2026
United States	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	150 MG	Nov 5, 2026
Australia	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	1 G	Nov 5, 2026
Poland	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	2 G	Nov 5, 2026
United States	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	100 MG	Nov 5, 2026
Norway	SAG21K	50 MG	Nov 5, 2026
United States	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	0.1 G	Nov 4, 2026
South Korea	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	300 MG	Nov 4, 2026
South Korea	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	300 MG	Nov 3, 2026
United States	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	1 G	Nov 3, 2026
Germany	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	100 MG	Nov 2, 2026
Canada	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	10 MG	Oct 29, 2026
Kosovo	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	1 G	Oct 25, 2026
Germany	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	200 MG	Oct 23, 2026
Singapore	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	1 G	Oct 20, 2026
Australia	3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	1 MT	Oct 20, 2026

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Product Name	Grade / Content	Price	Supplier Name	Details
High quality Sag21k factory direct supply at the lowest market price CAS 946002-48-8	Pharmaceutical Grade/99	$1/G FOB	Hubei Meisang Trading Co.,Ltd	Inquiry
cas 946002-48-8 3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(MethylaMino)cyclohexyl)benzo[b]thiophene-2-carboxaMide	Pharmaceutical Grade/99	$600-700/MT FOB	Ou Sheng International Trading Limited	Inquiry
Custom Chemical Pure 98% HPLC SAG21k SAG 21k Raw Powder CAS 946002-48-8	Pharmaceutical Grade/99	$1600-2000/G FOB	Xi'an Horlden Bio-Tech Co., Ltd	Inquiry
K21	/	$1/G EXW	Shaanxi Cuikang Pharmaceutical Technolog	Inquiry
SAG 21k 946002-48-8	Pharmaceutical Grade/99.99	$8-10/G FOB	Qingdao Orient Chemical Co.,LTD	Inquiry

SAG 21k, 3-chloro-4,7-difluoro-N-(2-Methoxy-5-(pyridin-4-yl)benzyl)-N-(4-(Methylamino)cyclohexyl)benzo[b]thiophene-2-carboxamide, CAS 946002-48-8

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