2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis
TDS
133627-45-9
Industrial Grade
99%
qingdao
OME
1kg/bag
Yes
2026-12-05
Chemicals,Glabridin,Phenylethyl Resorcinol,Ascorbyl Tetraisopalmitate,Alpha-Arbutin,Kojic Dipalmitate
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Product Details
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Seller Information
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Description
![Shop 2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis-Detailed Image 1]()
![Shop 2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis-Detailed Image 2]()
![Shop 2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis-Detailed Image 3]()
![Shop 2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis-Detailed Image 4]()
Product Name 3-Amino-2-chloro-4-methylpyridine CAS No. 133627-45-9 Appearance White to brown powder or crystalline solid Molecular Formula C6H7ClN2 Molecular Weight 142.59 g/mol ![Shop 2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis-Detailed Image 5]()
![Shop 2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis-Detailed Image 6]()
![Shop 2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis-Detailed Image 7]()
Product IntroductionProduct Introduction3‑Amino‑2‑chloro‑4‑methylpyridine, abbreviated as CAPIC, CAS 133627‑45‑9, is a chlorine‑containing heterocyclic pyridine fine chemical intermediate. It is generally pale yellow to off‑white crystalline solid with stable melting range, good solubility in organic solvents and slight solubility in water. Its molecular structure carries amino group, chlorine substituent and methyl group, offering abundant reactive sites for diazotization, coupling, amidation and nucleophilic substitution. It serves as a critical building block for targeted drugs, kinase inhibitors and JAK series compounds. Manufactured via refined synthetic route, it reaches HPLC purity up to 99% with strict impurity control and consistent batch quality, suitable for pharmaceutical research, process scale‑up and custom synthesis. It is not a cosmetic ingredient and shall not be incorporated into skincare or makeup formulas.ApplicationIt is widely used in leave‑on skincare products, especially anti‑aging brightening serums, creams, lotions, overnight repair oils and eye creams to ease dullness fine lines and dark circles. It can be compounded into sunscreen lotion gel and spray to reinforce overall UV defense and slow down photodegradation of sunscreen agents. It works well in facial masks ampoules and primers to defend against daytime environmental oxidation. It is also applied in body lotion and hair oil for antioxidative repair and retarding oil rancidity. It can be incorporated into skin‑friendly foundation and makeup to prevent discoloration and build luminous skin finish. It adopts mild recommended dosage and fits clean beauty concept. Easy to add in oil phase and compatible with diverse emulsification systems.Certifications![Shop 2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis-Detailed Image 8]()
Packing & Delivery![Shop 2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis-Detailed Image 9]()
![Shop 2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis-Detailed Image 10]()
FAQ1.Are you a factory or trading companyWe are a company integrating manufacturer and trading company
2.How is the quality I want to test.Before production and extraction, we will test all raw materials.Quality is our top priority. All products are strictly tested and confirmed by our QC and QA, approved by Third Party Lab in China.So you will be assured with Good Quality if you choose us. We welcome you test the product and hope to get your feedback.
3.Can I get a Free sampleYes, For most products we can provide you a free sample. Plesae be free to consult our salesman.For a larger quantity, we always support you with better price.
4. What's your main payment methodT/T (Bank transfer), WU, MoneyGram, Wechat,Alipay,Credit card payment.
5.What modes of transportation do you have to chooseWe cooperate with HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post ,sea transportation etc.And with the SAFE SHIPPING in each country, you can receive the goods smoothly.It is fast and safe method.
6.How is the goods packedWe usually send goods with disguise package outside and a double-layer sterile transparent bag inside.We have tried thousand of package methods, it looks serious and discreet.
7.How to proceed orderAfter you confirm all details of order, pay money in advance and give us Shipping address.We arrange the shipment at first time after receive payment and offer after-sales service after you receive parcel.
8.When will I receive the shipping number Where I can check status of my orderAfter the goods are sent out, our staff will send you the shipping number via email, online or WhatsApp ASAP.You can also check the status online on 17track.
Certificates-
![2-Chloro-3-amino-4-methylpyridine Heterocyclic Building Block For Kinase Inhibitor Synthesis Certificates 1]( "TDS")
TDS
Basic Info-
Product Name:
3-amino-2-chloro-4-methylpyridine
Other Name:3-Pyridinamine,2-chloro-4-methyl-;2-Chloro-4-methyl-3-pyridinamine;3-amino-2-chloro-4-methylpyridine;Capic;2-Chloro-4-methylpyridin-3-amine;2-Chloro-3-amino-4-methylpyridine
CAS No.:133627-45-9
Molecular Formula:C6H7ClN2
InChIKeys:InChIKey=UOBCYTOUXLAABU-UHFFFAOYSA-N
Molecular Weight:142.59
Exact Mass:142.59
EC Number:-0
DSSTox ID:DTXSID30373350
HScode:2933399090
Categories:
Characteristics-
PSA:
38.9
XLogP3:1.5
Appearance:off white crystals
Density:1.3±0.1 g/cm3
Melting Point:60-62 °C @ Solvent: Acetone
Boiling Point:283.3ºC at 760 mmHg
Flash Point:125.2±25.9 °C
Refractive Index:1.592
Storage Conditions:Room temperature.
Vapor Pressure:0.0229mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Serious eye damage, Category 1
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H318 Causes serious eye damage
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Chemicals,Glabridin,Phenylethyl Resorcinol,Ascorbyl Tetraisopalmitate,Alpha-Arbutin,Kojic Dipalmitate
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Location:
Room 805, No. 178 Yingchun Street, Laishan District, Yantai City, Shandong Province
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
20 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
5-10
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Year of Establishment:
2026
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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