Tirzepatide Raw Material Powder | High Purity Tirzepatide Supplier & Manufacturer

Tirzepatide, research code LY‑3298176, is a synthetic 39‑amino‑acid dual‑receptor agonist peptide, molecular formula C₂₂₅H₃₄₈N₄₈O₆₈ with molecular weight 4813.53 Da. Our offered material is research‑grade lyophilized powder, FOR LABORATORY RESEARCH USE ONLY. It is not intended for human administration, clinical diagnosis, therapy or animal treatment. This peptide is a widely‑used research tool for pharmaceutical companies, CRO laboratories, university research groups and biotech institutes, supporting in‑vitro cell assays, pre‑clinical mechanism studies, type‑2 diabetes and obesity‑related metabolic research as well as novel peptide drug discovery projects.
The product appears as white to off‑white lyophilized solid powder. Manufactured by advanced solid‑phase peptide synthesis and multi‑step chromatographic purification, HPLC verified purity reaches ≥98%. Each batch is accompanied with complete Certificate of Analysis (COA) and Mass Spectrometry (MS) test report to confirm molecular identity, ensuring consistent batch‑to‑batch performance and reproducible experimental data. Tirzepatide shows good water solubility and can be dissolved in pure water or PBS buffer to prepare working solutions for in‑vitro and in‑vivo lab studies. A fatty‑diacid side‑chain modification is introduced into its peptide backbone, which improves DPP‑IV resistance and extends circulating half‑life in biological test systems, reducing frequent dosing requirements for pre‑clinical model experiments.
As a first‑in‑class dual agonist, Tirzepatide activates both GLP‑1R (Glucagon‑like Peptide‑1 Receptor) and GIPR (Glucose‑dependent Insulinotropic Polypeptide Receptor) to produce synergistic metabolic effects, which differentiates it from single‑target GLP‑1 analogues. Activation of GLP‑1 receptor stimulates glucose‑dependent insulin release, suppresses glucagon secretion, reduces food intake and delays gastric emptying. GIP‑receptor activation further enhances insulin sensitivity and optimizes glycemic regulation. Published pharmacological data shows its EC₅₀ values against human GLP‑1R and GIPR, making it ideal for receptor binding tests, intracellular signal pathway exploration, glucose tolerance tests and obesity animal model research. Large numbers of pre‑clinical literatures demonstrate its functions in regulating food consumption, improving blood‑glucose profiles and modulating multiple metabolic biomarkers, providing valuable reference data for next‑generation anti‑diabetic and anti‑obesity drug development.
Multiple packaging sizes are available including 5mg, 10 mg, 15mg, 50 mg and 100 mg to cover small‑scale lab screening and medium‑volume research projects. For storage conditions: unopened lyophilized powder shall be kept hermetically sealed, dry and protected from light at ‑20 °C, shelf‑life 24 months; long‑term preservation is recommended at ‑80 °C. After reconstitution into aqueous solution, aliquot and store at ‑80 °C; strictly avoid repeated freeze‑thaw cycles which will degrade peptide bioactivity. Cold‑chain insulated packaging is adopted for international shipment to guarantee product quality upon arrival. After receiving goods, place vials into low‑temperature storage promptly. Vial opening operations are suggested to be performed under dry atmosphere to prevent moisture absorption and powder degradation.
Strict quality‑management procedures are implemented throughout production. Every production batch undergoes full‑item testing including HPLC purity detection, MS molecular‑weight confirmation, appearance inspection and moisture analysis. Full QC documentation can be provided upon customer request. As a global‑oriented B2B chemical‑research supplier, we support sample trial orders as well as bulk purchasing, matching procurement requirements of academic institutions, research centers and pharmaceutical R&D departments.
Important Notice: This product is FOR RESEARCH USE ONLY. Not for human or veterinary therapeutic and diagnostic purposes. All experimental manipulations must comply with local laboratory safety regulations.