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TNFR-Fc fusion protein

TNFR-Fc fusion protein structure

CAS No:
185243-69-0
Formula:
C2224H3475N621O698S36
Chemical Name:
TNFR-Fc fusion protein
Synonyms:
TNFR-Fc fusion protein;Etanercept;Embrel;Enbrel;Entanercept;1-235-TuMor necrosisfactor receptor (huMan) fusion protein with 236-467-iMMunoglobulin G1 (huMan g1-chain Fc fragMent) (9CI);rhuTNFR: Fc;rhu-TNFR-Fc
Categories:
Active Pharmaceutical Ingredients > Drugs Influencing Immune Function

Description

Etanercept (Enbrel) is a tumor necrosis factor (TNF) inhibitor used for treating rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and plaque psoriasis.

TNFR-Fc fusion protein Basic Attributes

Molecular Weight：

116.977

Exact Mass：

116.963

Characteristics

PSA：

58.2

Density：

2.326 g/cu cm

Melting Point：

200 deg C (with decomposition)

Water Solubility：

Readily soluble in mono- and diethanolamine

Storage Conditions：

Containers of vanadium shall be kept tightly closed at all times when not in use. Containers shall be stored in a safe manner to minimize accidental breakage, spillage, or contact with moisture. Combustible materials, such as finely ground vanadium carbide, vanadium aluminum alloys, vanadium metal, or ferrovanadium should be kept away from heat, sparks, or flames. /Vanadium compounds/

Safety Information

Transport codes：

2859

Stability/Shelf Life：

Stable under recommended storage conditions.

Precautionary statement(s)：

P201, P202, P260, P261, P264, P270, P271, P273, P281, P301+P310, P304+P312, P304+P340, P307+P311, P308+P313, P312, P314, P321, P330, P405, P501

Hazard Statements：

H301

Drug Function and Efficacy

none

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Etanercept for injection
Ingredients	Main ingredients: Etanercept Excipients: L-arginine hydrochloride, sodium chloride, sucrose, disodium hydrogen phosphate dihydrate, sodium dihydrogen phosphate dihydrate and water for injection. Source of active ingredients: Etanercept is a human tumor necrosis factor receptor p75Fc fusion protein produced by the Chinese hamster ovary (CHO) cell expression system. The dimer is composed of the extracellular ligand binding site of human tumor necrosis factor receptor 2 (TNFR2/p75) connected to the Fc fragment of human IgG1. The Fc of Etanercept includes CH2, CH3 and the connection site, but does not include the CH1 part of IgG1. Etanercept includes 934 amino acids and has a molecular weight of about 150kD.
Indication	none
Specifications	0.47 ml: 25 mg

Etanercept for injection
Specifications	25 mg/bottle

Etanercept Injection

Ingredients

Main ingredients: Etanercept Excipients: L-arginine hydrochloride, sodium chloride, sucrose, disodium hydrogen phosphate dihydrate, sodium dihydrogen phosphate dihydrate and water for injection. Source of active ingredients: Etanercept is a human tumor necrosis factor receptor p75Fc fusion protein produced by the Chinese hamster ovary (CHO) cell expression system. The dimer is composed of the extracellular ligand binding site of human tumor necrosis factor receptor 2 (TNFR2/p75) connected to the Fc fragment of human IgG1. The Fc of Etanercept includes CH2, CH3 and the connection site, but does not include the CH1 part of IgG1. Etanercept includes 934 amino acids and has a molecular weight of about 150kD.

Specifications

(0.94ml:50mg)*2

See More Related Drugs

Recommended Suppliers of TNFR-Fc fusion protein

Wuhan Biolab-reagent Biotechnology Co., LTD Contact Supplier

CN
1 YR

Business licensed

Trader Supplier of Antibody,Recombinant Protein,ELISA Kit

Research Grade Etanercept

CAS No.: 185243-69-0

Grade: Research Grade

Content: 95%

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