6-Isoquinolinamine,5-bromo-(9CI)

Synthesis of Compound 62; 1. 200 mg (1.35 mmol) of 6-aminoisoquinoline were disolved in 20 ml ofacetonitrile. 239, 568 mg (1 , 35 mmol) of N-bromsuccinimide was added. The reaction mixture was stirred for 4 h at room temperature. The reaction mixture was evaporated and dichloromethane was added. The organic phase was washed with water and dried. 224 mg of 5-brromo-isoquinolin-6-ylamine were obtained; HPLC/MS (B) 1.00 min, [M+H] 224.1. 200 mg (1.35 mmol) of 6-aminoisoquinoline were disolved in 20 ml of acetonitrile. 239, 568 mg (1, 35 mmol) of N-bromsuccinimide was added. The reaction mixture was stirred for 4 h at room temperature. The reaction mixture was evaporated and dichloromethane was added. The organic phase was washed with water and dried. 224 mg of

Molecular Weight:223.07
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:221.97926
Monoisotopic Mass:221.97926
Topological Polar Surface Area:38.9
Heavy Atom Count:12
Complexity:163
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes