 Home > Encyclopedia > Isoquinoline, 5-bromo-4-methyl-

Isoquinoline, 5-bromo-4-methyl-

Isoquinoline, 5-bromo-4-methyl- structure

CAS No:
651310-24-6
Formula:
C10H8BrN
Chemical Name:
Isoquinoline, 5-bromo-4-methyl-
Synonyms:
Isoquinoline,5-bromo-4-methyl-;5-Bromo-4-methylisoquinoline
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Request for Quotation

Isoquinoline, 5-bromo-4-methyl- Basic Attributes

Molecular Weight：

222.084

Exact Mass：

222.08

DSSTox ID：

DTXSID40621091

HScode：

2933499090

Characteristics

PSA：

12.9

XLogP3：

3.2

Density：

1.488±0.06 g/cm3(Predicted)

Boiling Point：

331.5°C at 760 mmHg

Flash Point：

154.263ºC

Refractive Index：

1.654

Safety Information

wgk germany：

hazard class code：

22-41

safety instructions：

26-39

Marks：

Precautionary statement(s)：

P264, P270, P280, P301+P312, P305+P351+P338, P310, P330, P501

Hazard Statements：

H302

GHS Classification：

|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P305+P351+P338, P310, P330, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Isoquinoline, 5-bromo-4-methyl- Use and Manufacturing

Intermediate X: 5-(2-Methoxy-4-(trifluoromethyl)phenyl)-4-methyl-l, 2, 3, 4- tetrahydroisoquinoline A solution of Cl2Pd(AmPhos) (Sigma-Aldrich, St. Louis, MO, 0.319 g, 0.450 mmol), 4-Methylisoquinoline (0.1 ml, synthesised according to the method described in Tetrahedron. Lett. 34, 45, 7239 (1993)) was dissolved in concentrated sulfuric acid (1 ml), then added with N-bromosuccinimide (125 mg) with ice cooling and stirred for 2 hours. The reaction mixture was added with 28% aqueous ammonia (5 ml) and extracted twice with dichloromethane (10 ml for each time). The organic layer was dried over anhydrous sodium sulfate, and then the solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (chloroform:methanol=50:1) to obtain the title compound (108 mg).

Computed Properties

Molecular Weight:222.08
XLogP3:3.2
Hydrogen Bond Acceptor Count:1
Exact Mass:220.98401
Monoisotopic Mass:220.98401
Topological Polar Surface Area:12.9
Heavy Atom Count:12
Complexity:160
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Isoquinoline, 5-bromo-4-methyl-

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

5-Bromo-4-methylisoquinoline

CAS No.: 651310-24-6

Content: 99.00%

Inquiry

Latest News on Isoquinoline, 5-bromo-4-methyl-

Learn More Other Chemicals

Hot Searches: propylene glycol prices; who sells the best peptides; where can you buy aniracetam; dioctyl phthalate prices; pippercillin; methylene diphenyl diisocyanate sds

Guide of Isoquinoline, 5-bromo-4-methyl-

Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
Learn More Other Chemicals

Isoquinoline, 5-bromo-4-methyl-

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.