4-Amino-6-bromoquinoline

A reaction flask with a stir bar was charged with 6-bromo-4-chloroquinoline 17 (500mg, 2.1mmol), acetamide (2.438g, 41.3mmol), and KA reaction flask with a stir bar was charged with 6-bromo-4-chloroquinoline 17 (500mg, 2.1mmol), acetamide (2.438g, 41.3mmol), and K2CO3 (1.449g, 10.5mmol). The mixture was heated to 180 C for 5 h and was allowed to cool to ambient temperature followed by adding water (50ml). The solution was extracted with ethyl acetate (20ml × 3), dried over Na2SO4, filtered, and concentrated. The residue was purified by silica gel chromatography (DCM:MeOH=20:1) to provide General procedure: To a round-bottom flask with stir bar was added General procedure: To a round-bottom flask with stir bar was added

Molecular Weight:223.07
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:221.97926
Monoisotopic Mass:221.97926
Topological Polar Surface Area:38.9
Heavy Atom Count:12
Complexity:163
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes