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trans-1-Cinnamylpiperazine

trans-1-Cinnamylpiperazine structure

CAS No:
87179-40-6
Formula:
C13H18N2
Chemical Name:
trans-1-Cinnamylpiperazine
Synonyms:
N-CINNAMYLPIPERAZINE;TRANS-1-CINNAMYLPIPERAZINE;TIMTEC-BB SBB000411;LABOTEST-BB LT00233225;1-TRANS-CINNAMYL PIPERAZINE;1-(3-PHENYL-ALLYL)-PIPERAZINE;1-(CINNAMYL)PIPERAZINE;1-((E)-3-PHENYLALLYL)PIPERAZINE
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Description

clear colorless to yellow liquid

trans-1-Cinnamylpiperazine is a piperazine derivative. It was used as a test compound to investigate the in vitro efficacy as an antiprotozoal against Philasterides dicentrarchi. It may be used to synthesize Incentrom A derivatives.

trans-1-Cinnamylpiperazine is an important organic synthetic reagent for the preparation of opioid tripeptides hybridised with trans-1-Cinnamylpiperazine, which exhibits low haematotoxicity and good cancer cell growth as an inhibitor of pancreatic cancer cell proliferation in two- and three-dimensional in vitro models Inhibition. It was also used in the preparation of the anticonvulsant active substance cinnamylpiperazine derivatives.

trans-1-Cinnamylpiperazine is a piperazine derivative.

trans-1-Cinnamylpiperazine Basic Attributes

Molecular Weight：

202.3

Exact Mass：

202.147003

BRN：

608984

EC Number：

673-639-1

Color/Form：

Pale Yellow

HScode：

29335995

Characteristics

PSA：

15.3

XLogP3：

2.05

Appearance：

clear to light yellow semi-solid

Density：

0.989 g/mL at 25 °C(lit.)

Melting Point：

39-44 °C(lit.)

Boiling Point：

129 °C1 mm Hg(lit.)

Flash Point：

>230 °F

Refractive Index：

1.574-1.576

PKA：

9.17±0.10(Predicted)

Critical Temperature & Pressure：

Refrigerator, under inert atmosphere

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

26-36-37/39

Marks：

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

36/37/38

trans-1-Cinnamylpiperazine Use and Manufacturing

Is an intermediate of medicine flunarizine hydrochloride

trans-1-Cinnamylpiperazine is used in the synthesis of bile acid piperazinyl derivatives which display pro-apoptotic properties on carcinoma human cell lines.

trans-1-Cinnamylpiperazine was used as a test compound to investigate thein vitroefficacy as an antiprotozoal againstPhilasterides dicentrarchi.It may be used to synthesize Incentrom A derivatives.

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CAS No.: 87179-40-6

Grade: Pharmaceutical Grade

Content: 99%

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CAS No.: 87179-40-6

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Guide of trans-1-Cinnamylpiperazine

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Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
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