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Home > Encyclopedia > 4-[(2R)-2-(Chloromethyl)-3-methylbutyl]-1-methoxy-2-(3-methoxypropoxy)benzene

4-[(2R)-2-(Chloromethyl)-3-methylbutyl]-1-methoxy-2-(3-methoxypropoxy)benzene

4-[(2R)-2-(Chloromethyl)-3-methylbutyl]-1-methoxy-2-(3-methoxypropoxy)benzene structure

4-[(2R)-2-(Chloromethyl)-3-methylbutyl]-1-methoxy-2-(3-methoxypropoxy)benzene 

structure
  • CAS No:

    324763-39-5

  • Formula:

    C17H27ClO3

  • Chemical Name:

    4-[(2R)-2-(Chloromethyl)-3-methylbutyl]-1-methoxy-2-(3-methoxypropoxy)benzene

  • Synonyms:

    Benzene,4-[(2R)-2-(chloromethyl)-3-methylbutyl]-1-methoxy-2-(3-methoxypropoxy)-;4-[(2R)-2-(Chloromethyl)-3-methylbutyl]-1-methoxy-2-(3-methoxypropoxy)benzene;2-(3-methoxypropoxy)-4-[(R)-2-(chloromethyl)-3-methylbutyl]-1-methoxybenzene;(R)-4-(2-(Chloromethyl)-3-methylbutyl)-1-methoxy-2-(3-methoxypropoxy)benzene

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

4-[(2R)-2-(Chloromethyl)-3-methylbutyl]-1-methoxy-2-(3-methoxypropoxy)benzene Basic Attributes

314.85

314.85

608-745-9

DTXSID20466306

2909309090

Characteristics

27.7

4.55

1.034

398 ºC

122 ºC

1.491

4-[(2R)-2-(Chloromethyl)-3-methylbutyl]-1-methoxy-2-(3-methoxypropoxy)benzene Use and Manufacturing

4-[(2R)-2-(Chloromethyl)-3-methylbutyl]-1-methoxy-2-(3-methoxypropoxy)benzene is an intermediate in the preparation of orally active renin inhibitor Aliskiren (A536000).

Computed Properties

Molecular Weight:314.8
XLogP3:4.5
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:10
Exact Mass:314.1648724
Monoisotopic Mass:314.1648724
Topological Polar Surface Area:27.7
Heavy Atom Count:21
Complexity:260
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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