Coenzyme B12
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Coenzyme B12
structure -
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CAS No:
13870-90-1
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Formula:
C72H100CoN18O17P
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Chemical Name:
Coenzyme B12
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Synonyms:
Cobinamide,Co-(5′-deoxyadenosin-5′-yl)-,f-(dihydrogen phosphate),inner salt,3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3);Cobinamide,Co-(5′-deoxyadenosine-5′) deriv.,hydroxide,dihydrogen phosphate (ester),inner salt,3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole;Cobinamide,Co-(5′-deoxyadenosine-5′) deriv.,hydroxide,dihydrogen phosphate (ester),inner salt,3′-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole;Cobalamin,Co-(5′-deoxy-5′-adenosyl)-;Cobalamin coenzyme;Coenzyme B12;DBC coenzyme;5′-Deoxyadenosylcobalamin;5′-Deoxyadenosyl-5,6-dimethylbenzimidazolylcobamide;α-(5,6-Dimethylbenzimidazolyl)cobamide coenzyme;Vitamin B12 coenzyme;Cobamide coenzyme,(5′-deoxy-5′-adenosyl)-;Dibencozide;Vitamin B12,Co-(5′-deoxy-5′-adenosyl) deriv.;5′-Deoxyadenosyl vitamin B12;(5′-Deoxy-5′-adenosyl)cobamide coenzyme;α-(5,6-Dimethylbenzimidazolyl)-Co-5′-deoxyadenosylcobamide;(5,6-dimethylbenzimidazolyl)cobamide coenzyme;Cobamide,Co-(5′-deoxy-5′-adenosyl)-α-(5,6-dimethyl-1H-benzimidazolyl)-;Cobamide coenzyme,(5,6-dimethyl-1H-benzimidazolyl)-;Cobamamide;5,6-Dimethylbenzimidazolyl-Co-5′-deoxyadenosylcobamide;Adenosylcobalamin;5′-Deoxy-5′-adenosylcobalamin;5-Deoxyadenosylcobalamin;Deoxyadenosylcobalamin;Funacomide;Calomide;Actimide;Cobazymase;Betarin;Dolonevran;Hi-Fresmin;DBC;Anabasi;Adenosyl B12;Represil;Enzicoba;Dibenzcozamide;Dimebenzcozamide;LM 176;14038-92-7;14729-85-2;14752-55-7;15671-19-9;17000-53-2;56713-24-7;59158-58-6;94188-06-4;210780-01-1
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CAS No:
Description
ChEBI: A member of the class of cobalamins that is vitamin B12 in which the cyano group is replaced by a 5'-deoxyadenos-5'-yl moiety. It is one of the two metabolically active form of vitamin B12.
Coenzyme B12 Basic Attributes
1579.58
1578.658325
237-627-6
DTXSID1046009
B - Blood and blood forming organs
2936260000
Computed Properties
Molecular Weight:1579.6
Hydrogen Bond Donor Count:12
Hydrogen Bond Acceptor Count:27
Rotatable Bond Count:17
Exact Mass:1578.658339
Monoisotopic Mass:1578.658339
Topological Polar Surface Area:571
Heavy Atom Count:109
Complexity:3730
Defined Atom Stereocenter Count:13
Undefined Atom Stereocenter Count:5
Defined Bond Stereocenter Count:3
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
Drug Function and Efficacy
A similar substance of cyanocobalamin B12. It is an important coenzyme for the synthesis of nucleotides in cells, participates in methyl conversion and folic acid metabolism in the body, and promotes the reduction of methylfolate to tetrahydrofolate; it also participates in the tricarboxylic acid cycle, is very important for the formation of lipoproteins in nerve myelin, and can keep sulfhydryl enzymes in an active state, thereby participating in a wide range of protein and fat metabolism. It can promote the development and maturation of red blood cells, and is a necessary factor for the complete formation of nerve sheath spinal cord fibers and maintaining the function of epithelial cells in the digestive system.
Registered Holders
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North China Pharmaceutical Group Hualuan Co., Ltd.
Active
China
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Ningxia Kingvit Pharmaceutical Co., Ltd.
Active
China
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Hebei North China Pharmaceutical HUAHENG Pharmaceutical Co., Ltd.
Active
China
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