 Home > Encyclopedia > 3-Quinolineboronic acid

3-Quinolineboronic acid

3-Quinolineboronic acid structure

CAS No:
191162-39-7
Formula:
C9H8BNO2
Chemical Name:
3-Quinolineboronic acid
Synonyms:
CHEMBRDG-BB 4003837;3-QUINOLINEBORONIC ACID;3-QUINOLYL BORONIC ACID;3-QUINOLINYLBORONI ACID;3-QUINOLINYLBORONIC ACID;AKOS BRN-0151;RARECHEM AK VD 0023;QUINOLIN-3-YLBORONIC ACID
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Request for Quotation

Description

light pink or orange to light brown powder

3-Quinolineboronic acid Basic Attributes

Molecular Weight：

172.98

Exact Mass：

173.064804

BRN：

8764547

EC Number：

DSSTox ID：

DTXSID60370433

HScode：

29334900

Characteristics

PSA：

53.4

XLogP3：

-0.08540

Appearance：

Light pink or orange to light brown Powder

Density：

1.28±0.1 g/cm3(Predicted)

Melting Point：

148-155°C

Boiling Point：

400.3±37.0 °C(Predicted)

Flash Point：

195.9±26.5 °C

Refractive Index：

1.645

Storage Conditions：

Keep Cold

Vapor Pressure：

0.066mmHg at 25°C

Safety Information

Hazard category：

IRRITANT, KEEP COLD

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38-22

safety instructions：

36/37/39-26-22-37-36

Marks：

Xn,Xi

Hazard note：

Irritant

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 47 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

3-Quinolineboronic acid Use and Manufacturing

Methods of Manufacturing

General procedure: To a two-neck 250mL round bottom flask, triisopropyl borate (3.30mL, 29.06mmol) and 3-bromoquinoline (3.00g, 14.49mmol) was dissolved in dry THF (100mL), then n-butyllithium (14.50mL of a 2M solution in hexane, 29.00mmol) was added dropwise via a dropping funnel over 1h under NCompound 3-bromo-quinoline (3-bromoquinoline) 10g (48.06mmol) and triisopropylborate (triisopropylborate) 22mL (96.13mmol) dissolved in 200mL of THF and then, at -75 ° C n-BuLi 53mL (96.13mmol) of It was added slowly. After stirring at ° C or less for 20 minutes into the 2N HCl, it was adjusted to pH 7 neoteumyeonseo a 5NNaOH slowly. Ethyl acetate (Ethyl acetate) and was extracted with distilled water, methanol and recrystallization conducted by removing water to give the title compound21-45.95g (72percent).To a solution of compound 3-bromoquinoline (2.08 g, 10 mmol), triisopropyl borate (2.3g, 12 mmol) in THF (20 mL) was added n-BuLi (4 mL, 2.5 M in hexane) at -78PREPARATION 98

Uses

Reactant for: Preparation of P1-substituted symmetry-based human immunodeficiency virus protease inhibitors with antiviral activity against drug-resistant viruses Preparation of heterobiaryls via Suzuki-Miyaura cross-coupling with heteroaryl halides in co

Computed Properties

Molecular Weight:172.98
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:173.0648087
Monoisotopic Mass:173.0648087
Topological Polar Surface Area:53.4
Heavy Atom Count:13
Complexity:177
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 3-Quinolineboronic acid

Xi'an Horlden Bio-Tech Co., Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide,KY19382,5-deazaflavin,Dihexa,Urolithin A

3-Quinolineboronic acid cas191162-39-7[Consult customer service]

CAS No.: 191162-39-7

Grade: Consult customer service

Inquiry
NATURE INDUSTRIAL LIMITED Contact Supplier

HK
2 YRS

Business licensed

Trader Supplier of Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332,Orforglipron,Pharmaceutical intermediates,Aniracetam,Paraxanthine,AF710B,Clascoterone,TAK-653,PRL-8-53

3-Quinolineboronic acid CAS: 191162-39-7

Unit Price: $1250 /KG FOB

CAS No.: 191162-39-7

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
HK Technology Development Co., Ltd. Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of piperidine,Piperazine,pyrrolidine,amino acids

Quinoline-3-boronic acid 99.5% White

CAS No.: 191162-39-7

Grade: Pharmaceutical Grade

Content: 99.5%

Inquiry