SYR-472
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SYR-472
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CAS No:
1029877-94-8
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Formula:
C18H20FN5O2.C4H6O4
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Chemical Name:
SYR-472
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Synonyms:
SYR-472 succinate;Trelagliptin Succinate (SYR-472);SYR 111472 succinate;Trelagliptin succinat;SYR-472 Trelagliptin succinat;Trelagliptin succinate(SRY-472);Trelagliptin succinateSYR 111472 succinate;SRY-472
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CAS No:
Description
Trelagliptin(SYR-472) is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). IC50 value:Target: DPP4Two Phase II clinical studies have been completed with Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus. Phase III clinical studies with trelagliptin in Japan to evaluate its safety and efficacy in a once-weekly oral treatment regimen. Currently, all available DPP-4 inhibitors are dosed once-dail
Computed Properties
Molecular Weight:475.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:475.18671173
Monoisotopic Mass:475.18671173
Topological Polar Surface Area:168
Heavy Atom Count:34
Complexity:750
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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