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Home > Encyclopedia > 1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1)

1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1)

1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1) structure

1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1) 

structure
  • CAS No:

    172895-15-7

  • Formula:

    C21H24N2O2.ClH

  • Chemical Name:

    1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1)

  • Synonyms:

    1H-Pyrido[3,4-b]indole,1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-,hydrochloride (1:1);1H-Pyrido[3,4-b]indole,1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-,monohydrochloride;LY 272015;159729-69-8

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1) Basic Attributes

372.893

372.16000

DTXSID30432996

Characteristics

46.3

5.05380

Store at +4°C

1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1) Use and Manufacturing

High affinity 5-HT 2B receptor antagonist that displays selectivity over 5-HT 2A and 5-HT 2C receptors (K i values are 0.75, 21.63 and 28.7 nM for 5-HT 2B , 5-HT 2C and 5-HT 2A receptors respectively). Orally active.

Computed Properties

Molecular Weight:372.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:372.1604557
Monoisotopic Mass:372.1604557
Topological Polar Surface Area:46.3
Heavy Atom Count:26
Complexity:446
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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