1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1)
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1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1)
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CAS No:
172895-15-7
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Formula:
C21H24N2O2.ClH
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Chemical Name:
1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1)
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Synonyms:
1H-Pyrido[3,4-b]indole,1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-,hydrochloride (1:1);1H-Pyrido[3,4-b]indole,1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-,monohydrochloride;LY 272015;159729-69-8
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CAS No:
1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1) Basic Attributes
372.893
372.16000
DTXSID30432996
1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1) Use and Manufacturing
High affinity 5-HT 2B receptor antagonist that displays selectivity over 5-HT 2A and 5-HT 2C receptors (K i values are 0.75, 21.63 and 28.7 nM for 5-HT 2B , 5-HT 2C and 5-HT 2A receptors respectively). Orally active.
Computed Properties
Molecular Weight:372.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:372.1604557
Monoisotopic Mass:372.1604557
Topological Polar Surface Area:46.3
Heavy Atom Count:26
Complexity:446
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1)
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