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Mivacurium chloride

Mivacurium chloride structure

CAS No:
106861-44-3
Formula:
C58H80N2O14.2Cl
Chemical Name:
Mivacurium chloride
Synonyms:
Isoquinolinium,2,2′-[[(4E)-1,8-dioxo-4-octene-1,8-diyl]bis(oxy-3,1-propanediyl)]bis[1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-,chloride (1:2),(1R,1′R)-;Isoquinolinium,2,2′-[(1,8-dioxo-4-octene-1,8-diyl)bis(oxy-3,1-propanediyl)]bis[1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-,dichloride,[R-[R*,R*-(E)]]-;Isoquinolinium,2,2′-[[(4E)-1,8-dioxo-4-octene-1,8-diyl]bis(oxy-3,1-propanediyl)]bis[1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-,dichloride,(1R,1′R)-;[R-[R*,R*-(E)]]-2,2′-[(1,8-Dioxo-4-octene-1,8-diyl)bis(oxy-3,1-propanediyl)]bis[1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]isoquinolinium dichloride;BW-B 1090U;Mivacurium chloride;Mivacron;BW B1090U dichloride
Categories:
Active Pharmaceutical Ingredients > Anesthetic Agents

Description

Off-White SolidMivacurium chloride,a mixture of three stereoisomers, is an intravenously administered, short-acting skeletal muscle relaxant introduced as an adjunct to general anesthesia. Structurally mivacurium chloride is closely related to doxacurium chloride introduced in 1991 by Wellcome as a muscle relaxant. It is a nondepolarizing neuromuscular blocking agent reportedly with a shorter duration of action and a more rapid rate of spontaneous recovery than other nondepolarizing agents

Mivacurium chloride Basic Attributes

Molecular Weight：

1100.17

Exact Mass：

1098.50000

EC Number：

1312995-182-4

DSSTox ID：

DTXSID5046649

Characteristics

PSA：

144.90000

XLogP3：

2.95460

Storage Conditions：

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Specific rotation：

20D -62.7° (c = 1.9 in water)

Safety Information

GHS Classification：

|Danger|H301 (98.04%): Toxic if swallowed [Danger Acute toxicity, oral]|P264, P270, P301+P310, P321, P330, P405, and P501|Aggregated GHS information provided by 51 companies from 3 notifications to the ECHA C&L Inventory.

Mivacurium chloride Use and Manufacturing

Non-depolarizing neuromuscular blocking agent. Muscle relaxant (skeletal)

Computed Properties

Molecular Weight:1100.2
Hydrogen Bond Acceptor Count:16
Rotatable Bond Count:30
Exact Mass:1098.4986606
Monoisotopic Mass:1098.4986606
Topological Polar Surface Area:145
Heavy Atom Count:76
Complexity:1550
Defined Atom Stereocenter Count:2
Undefined Atom Stereocenter Count:2
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Muscle relaxants

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Mivacurium Injection
Specifications	10ml:20mg

Mivacurium Injection
Specifications	10 ml: 20 mg

Mivacurium Injection
Specifications	10ml:20mg

See More Related Drugs

Registered Holders

Luzhou Kereide Pharmaceutical Co., Ltd.

China
Active
FARMABIOS S.P.A.

Italy
Active
UNION QUIMICO FARMACEUTICA SA

Spain
Active

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Recommended Suppliers of Mivacurium chloride

Shandong Airuike Chemical Co., Ltd. Contact Supplier

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Mivacurium chloride 106861-44-3

CAS No.: 106861-44-3

Grade: Pharmaceutical Grade

Content: 99%

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NewRoute Pharma Contact Supplier

CN
3 YRS

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Mivacurium chloride

CAS No.: 106861-44-3

Grade: Pharmaceutical Grade

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