Hydrocortisone butyrate
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Hydrocortisone butyrate
structure -
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CAS No:
13609-67-1
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Formula:
C25H36O6
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Chemical Name:
Hydrocortisone butyrate
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Synonyms:
Pregn-4-ene-3,20-dione,11,21-dihydroxy-17-(1-oxobutoxy)-,(11β)-;Cortisol,17-butyrate;Butyric acid,17-ester with cortisol;(11β)-11,21-Dihydroxy-17-(1-oxobutoxy)pregn-4-ene-3,20-dione;Hydrocortisone 17-butyrate;Hydrocortisone 17α-butyrate;Locoid;Hydrocortisone butyrate;4-Pregnene-11β,21-dihydroxy-17α-butyryloxy-3,20-dione;Alfason;Laticort;Plancol;82632-85-7
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Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System
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CAS No:
Hydrocortisone butyrate Basic Attributes
432.55
432.55
237-093-4
DTXSID4045896
D - Dermatologicals
2937290000
Characteristics
101
2.81
1.0914 (rough estimate)
217-220 °C
466.2°C (rough estimate)
194.0±23.6 °C
1.4593 (estimate)
Safety Information
NONH for all modes of transport
2
GM9002000
P201, P202, P260, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P308+P313, P312, P314, P321, P322, P330, P332+P313, P337+P313, P362, P363, P405, P501
H302+H312+H332
|Warning|H302+H312+H332 (20%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]|P201, P202, P260, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P308+P313, P312, P314, P321, P322, P330, P332+P313, P337+P313, P362, P363, P405, and P501|Aggregated GHS information provided by 6 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hydrocortisone butyrate Use and Manufacturing
Hydrocortisone Butyrate is a topical corticosteroid use to treat a variety of dermatological conditions. It acts as an antiinflammatory, antiproliferative and immunosuppresive agent.
Computed Properties
Molecular Weight:432.5
XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:432.25118886
Monoisotopic Mass:432.25118886
Topological Polar Surface Area:101
Heavy Atom Count:31
Complexity:817
Defined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
This product is a glucocorticoid drug, which has anti-inflammatory, anti-allergic, antipruritic and exudation-reducing effects when used externally.
Registered Holders
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Chongqing Shengkai Pharmaceutical Co., Ltd.
Active
China
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Jinyao Pharmaceutical Co., Ltd.
Active
China
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Henan LIHUA Pharmaceutical Co., Ltd.
Active
China
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