Spectinomycin dihydrochloride pentahydrate
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Spectinomycin dihydrochloride pentahydrate
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CAS No:
22189-32-8
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Formula:
C14H24N2O7.2ClH.5H2O
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Chemical Name:
Spectinomycin dihydrochloride pentahydrate
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Synonyms:
4H-Pyrano[2,3-b][1,4]benzodioxin-4-one,decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-,hydrochloride,hydrate (1:2:5),(2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-;4H-Pyrano[2,3-b][1,4]benzodioxin-4-one,decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-,dihydrochloride,pentahydrate;4H-Pyrano[2,3-b][1,4]benzodioxin-4-one,decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-,dihydrochloride,pentahydrate,[2R-(2α,4aβ,5aβ,6β,7β,8β,9α,9aα,10aβ)]-;4H-Pyrano[2,3-b][1,4]benzodioxin-4-one,decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-,dihydrochloride,pentahydrate,(2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-;Spectinomycin dihydrochloride pentahydrate;Spectinomycin hydrochloride hydrate;11034-37-0
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Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs
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CAS No:
Description
Spectinomycin dihydrochloride pentahydrate is a broad-spectrum aminocyclitol antibiotic that inhibits the growth of a variety of gram-positive and gram-negative organisms.
Characteristics
130
-2.3
white to off-white powder
205-207° (dec)
583.1°C at 760 mmHg
306.4ºC
soluble in water.soluble in water, methanol, dimethyl sulfoxide, ethanol and dimethyl formamide.H2O: 50 mg/mL, clear, faintly yellow
2-8°C
5.05E-16mmHg at 25°C
D +14.8° (c = 0.42 in water)
6.95None
Spectinomycin dihydrochloride pentahydrate Use and Manufacturing
Spectinomycin is an aminocyclitol antibiotic produced by S. spectabilis that is active against Gram-negative and Gram-positive bacteria. Spectinomycin inhibits protein synthesis by binding to the 30S ribosomal subunit and interfering with peptidyl tRNA translocation. Mutations in the gene for ribosomal protein S5 prevents binding of spectinomycin and contributes to bacterial resistance.
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Spectinomycin dihydrochloride pentahydrate
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