Pirenoxine sodium
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Pirenoxine sodium
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CAS No:
51410-30-1
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Formula:
C16H8N2O5.Na
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Chemical Name:
Pirenoxine sodium
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Synonyms:
5H-Pyrido[3,2-a]phenoxazine-3-carboxylic acid,1-hydroxy-5-oxo-,sodium salt (1:1);5H-Pyrido[3,2-a]phenoxazine-3-carboxylic acid,1-hydroxy-5-oxo-,monosodium salt;Sodium 1-hydroxy-5-oxo-5H-pyrido[3,2-a]phenoxazine-3-carboxylate;Catalin sodium;Pirenoxine sodium;Pirfenoxone sodium salt
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CAS No:
Characteristics
108
0.91010
1.7g/cm3
515.8ºC at 760mmHg
265.7ºC
LD50 in mice (mg/kg): >10000 orally; >5000 s.c.; 2120-2250 i.p. LD50 in rats (mg/kg) i.p.: 2400 (males); 1460 (females) (Ikemoto)
Computed Properties
Molecular Weight:330.23
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:330.02526561
Monoisotopic Mass:330.02526561
Topological Polar Surface Area:108
Heavy Atom Count:24
Complexity:777
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Pirenoxine sodium can competitively inhibit the effects of quinone substances on lens soluble proteins, and can also fight against cataracts caused by free radical damage to the lens, and has a certain inhibitory effect on the development of cataracts. Animal experiments have shown that pirenoxine sodium can reduce the incidence of posterior capsule opacity after extracapsular cataract extraction.
Registered Holders
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Lesheng Pharmaceutical Shijiazhuang Co., Ltd.
Active
China
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Hubei Zhongjiachem Pharmaceutical Co., Ltd.
Active
China
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Qianjiang Yongan Pharmaceutical Co., Ltd.
Active
China
Recommended Suppliers of Pirenoxine sodium
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CN
5 YRS
Business licensedDistributor Supplier of DIMETHYL SULFOXIDE,NMP,MMTInquiryUnit Price: $2100-2300 /MT FOBCAS No.: 51410-30-1Content: 99%
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