 Home > Encyclopedia > Lorcainide hydrochloride

Lorcainide hydrochloride

Lorcainide hydrochloride structure

CAS No:
58934-46-6
Formula:
C22H27ClN2O.ClH
Chemical Name:
Lorcainide hydrochloride
Synonyms:
Benzeneacetamide,N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]-,hydrochloride (1:1);Benzeneacetamide,N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]-,monohydrochloride;R 15889;Ro 13-1042;Lorcainide hydrochloride;Lorivox;Remivox;Lopantrol
Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs

Request for Quotation

Lorcainide hydrochloride Basic Attributes

Molecular Weight：

407.37652

Exact Mass：

406.15800

EC Number：

261-504-6

Characteristics

PSA：

23.55000

XLogP3：

5.52840

Melting Point：

263 °C

Boiling Point：

503ºC at 760 mmHg

Flash Point：

258ºC

Safety Information

Transport codes：

NONH for all modes of transport

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

Drug Information

MeSH：

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

MeSH Entry Terms：

4'-chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide

Lorcainide hydrochloride Use and Manufacturing

Cardiac depressant (anti-arrhythmic).

Computed Properties

Molecular Weight:407.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:406.1578689
Monoisotopic Mass:406.1578689
Topological Polar Surface Area:24.8
Heavy Atom Count:27
Complexity:433
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes