CHRYSOMYCIN B
-
CHRYSOMYCIN B
structure -
-
CAS No:
83852-56-6
-
Formula:
C27H28O9
-
Chemical Name:
CHRYSOMYCIN B
-
Synonyms:
4-(6-Deoxy-3-C-methyl-beta-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-6H-benzo[d]naphtho[1,2-b]pyran-6-one;B,ChrysoMycin;ChrysoMycin M, VirenoMycin M, Albacarcin M;6H-Benzo[d]naphtho[1,2-b]pyran-6-one,4-(6-deoxy-3-C-methyl-b-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl- (9CI)
- Categories:
-
CAS No:
Characteristics
138.82000
4.99
solid
1.41
784.0±60.0 °C at 760 mmHg
265.9±26.4 °C
1.663
DMF: soluble
2-8°C
CHRYSOMYCIN B Use and Manufacturing
Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin B, containing a methyl group in the 8-position, is less active than its vinyl analogue (Chrysomycin A), albeit still a potent antitumor active and an inhibitor of the catalytic activity of human topoisomerase II. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated cross-linkers of DNA to histones.
Computed Properties
Molecular Weight:496.5
XLogP3:2.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:3
Exact Mass:496.17333247
Monoisotopic Mass:496.17333247
Topological Polar Surface Area:135
Heavy Atom Count:36
Complexity:823
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Learn More Other Chemicals
-
Saquayamycin B
99260-67-0
-
Fumitremorgin B
12626-17-4
-
dehydrobruceine B
53730-90-8
-
(-)-6-Deoxyerythronolide B Formula
15797-36-1
-
cyanosafracin B Formula
96996-50-8
-
3''-Deoxyrubradirin B Formula
69279-50-1
-
Epelmycin B Structure
107807-24-9
-
Rubrofusarin B Structure
17276-15-2
-
What is CARATUBERSIDE B
119767-18-9
-
What is 7-Hydroxyaloin B
82461-12-9