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Chrysophanol

Chrysophanol structure

CAS No:
481-74-3
Formula:
C15H10O4
Chemical Name:
Chrysophanol
Synonyms:
9,10-Anthracenedione,1,8-dihydroxy-3-methyl-;Anthraquinone,1,8-dihydroxy-3-methyl-;1,8-Dihydroxy-3-methyl-9,10-anthracenedione;C.I. 75400;Chrysophanic acid;Chrysophanol;C.I. Natural Yellow 23;1,8-Dihydroxy-3-methylanthraquinone;3-Methylchrysazin;3-Methyl-1,8-dihydroxyanthraquinone;Turkey Rhubarb;2-Methyl-4,5-dihydroxyanthraquinone;4,5-Dihydroxy-2-methylanthraquinone;1,8-Dihydroxy-3-methyl-9,10-anthraquinone;NSC 37132;NSC 646567
Categories:
Biochemical Engineering > Plant Extracts

Description

Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K.

Chrysophanol Basic Attributes

Molecular Weight：

254.24

Exact Mass：

254.24

EC Number：

207-572-2

HScode：

2942000000

Characteristics

PSA：

74.6

XLogP3：

3.5

Appearance：

yellow-orange

Density：

1.5±0.1 g/cm3

Melting Point：

196 °C

Boiling Point：

489.5°C at 760 mmHg

Flash Point：

263.9±25.2 °C

Refractive Index：

1.710

Water Solubility：

H2O: <0.1 g/100 mL at 18 ºC;chloroform: soluble 1%

Storage Conditions：

2-8°C

Vapor Pressure：

3.69X10-10 mm Hg at 25 °C (est)

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/38-36/37/38

safety instructions：

26-36-37/39

RTECS Number：

CB6725000

Marks：

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents.

Precautionary statement(s)：

P305 + P351 + P338

Hazard Statements：

H315-H319

Chrysophanol Use and Manufacturing

A topical ointment used in the treatment of dermal conditions such as eczema and herpes.

Computed Properties

Molecular Weight:254.24
XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Exact Mass:254.05790880
Monoisotopic Mass:254.05790880
Topological Polar Surface Area:74.6
Heavy Atom Count:19
Complexity:405
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Stop bleeding and improve microcirculation

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Huanglian Shuangqing Pills
Ingredients	Coptis chinensis, gypsum, licorice, scutellaria baicalensis, rhubarb, red peony root, gardenia, forsythia, angelica, ligusticum chuanxiong, mint, schizonepeta, chrysanthemum, scrophularia, radix trichosanthis, platycodon.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	Each 10 pills weigh 0.35g
Manufacturer	Shanxi Lvliang Traditional Chinese Medicine Factory

Regeneration Pills
Ingredients	Atractylodes macrocephala, Angelica dahurica, leopard bone, borneol, cardamom, agarwood, red peony root, Chuanxiong, pangolin, rhubarb, angelica, earthworm, cardamom, windproof, powdered radix strychnifoliae, Poria, aconite, licorice, kudzu root, bone drynaria, patchouli, tortoise shell, Polygonum multiflorum, red yeast rice, red tangerine peel, coptis root, astragalus, Jianqu, silkworm, two-pointed, ephedra, myrrh, mother clove, bezoar, turmeric, aconite meat, notopterygium, green peel, scorpion, ginseng, cinnamon, frankincense, Panax notoginseng, mistletoe, musk, Rehmannia root, buffalo horn concentrate powder, sandalwood, Gastrodia elata, Tianzhuhuang, Clematis, Linderae sibiricum, asarum, Cyperus rotundus, Scrophularia ningpoensis, Sanguisorba officinalis, pine knot, cinnabar
Indication	Not yet clear
Specifications	Each pill weighs 9g
Manufacturer	Shanxi Daningtang Pharmaceutical Co., Ltd.

Children's Baixiao Tablets
Ingredients	Antelope horn, buffalo horn concentrated powder, bezoar, borneol, honeysuckle, forsythia, Uncaria rhubarb, rhubarb, Fritillaria cirrhosa, rhubarb, cinnabar, realgar, etc.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	Each tablet weighs 0.2g
Manufacturer	Liaoning Haiyi Pharmaceutical Co., Ltd.

See More Related Drugs

Recommended Suppliers of Chrysophanol

Wuhan Pnq Int Trade Co., Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Apigenin,PQQ,NMNH

PNQ supply Chrysophanol CAS 481-74-3

Unit Price: $3.5-4 /MT FOB

CAS No.: 481-74-3

Grade: Chemical Grade

Content: 99%

Inquiry
Wuhan Oner Biotech Co.,Ltd. Contact Supplier

CN
6 YRS

Business licensed

Distributor Supplier of Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

Buy Rhubarb Root Extract 98% Chrysophanol Chrysophanic Acid Powder

Unit Price: $10.1-11.11 /KG FOB

CAS No.: 481-74-3

Grade: Food Grade

Content: 98%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

Chrysophanic acid 99% see COA Kanbei kanbei

CAS No.: 481-74-3

Grade: Industrial Grade

Content: 99%

Inquiry

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Guide of Chrysophanol

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Drug Function and Efficacy
Related Drugs
Recommended Suppliers
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