HYDROXYCITRIC ACID LACTONE, (-)-(P)
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HYDROXYCITRIC ACID LACTONE, (-)-(P)
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CAS No:
27750-13-6
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Formula:
C6H6O7
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Chemical Name:
HYDROXYCITRIC ACID LACTONE, (-)-(P)
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Synonyms:
HYDROXYCITRIC ACID LACTONE, (-)-(P);3-C-Carboxy-2-deoxy-D-erythropentaric acid 1,4-lactone;Garcinia lactone;(2S,3S)-3-Hydroxy-5-oxotetrahydrofuran-2,3-dicarboxylic acid
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CAS No:
Description
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis[1][2].
(+)-garcinia acid is a butan-4-olide and a hydroxy carboxylic acid. It has a role as a metabolite.
Computed Properties
Molecular Weight:190.11
XLogP3:-1.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:190.01135253
Monoisotopic Mass:190.01135253
Topological Polar Surface Area:121
Heavy Atom Count:13
Complexity:283
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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HYDROXYCITRIC ACID LACTONE, (-)-(P)
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