Euphorbia factor L1
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Euphorbia factor L1
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CAS No:
76376-43-7
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Formula:
C32H40O8
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Chemical Name:
Euphorbia factor L1
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CAS No:
Description
Euphorbia Factor L1 is a diterpenoid from Euphorbia lathyris L., reduces the expression of Bcl-2, PI3K, AKT and mTOR protein and mRNA, upregulates cleaved caspase-9 and caspase-3 levels, buts shows no effect on pro-caspase-9 and pro-caspase-3. Euphorbia Factor L1 induces apoptosis, has anticancer, antiadipogenesis, antiosteoclastogenesis and multidrug resistance-modulating effect[1].
Characteristics
108.50000
5.55
1.2±0.1 g/cm3
201 - 203 °C
633.1±55.0 °C at 760 mmHg
263.9±31.5 °C
1.566
Computed Properties
Molecular Weight:552.7
XLogP3:4.7
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:8
Exact Mass:552.27231823
Monoisotopic Mass:552.27231823
Topological Polar Surface Area:109
Heavy Atom Count:40
Complexity:1090
Defined Atom Stereocenter Count:8
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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