Phosphorofluoridic acid

99.99

99.99

IW87A7KU3R

1776

DTXSID1075309

COLORLESS LIQUID

57.5

0.04860

yellow liquid

1.818 g/cm³ @ Temp: 25 °C

SOL IN ALL PROPORTIONS IN COLD WATER

MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMP INTO TOXIC COMPONENTS SHOULD BE STORED IN COOL, WELL-VENTILATED PLACE, OUT OF DIRECT RAYS OF SUN, AWAY FROM FIRE HAZARD & PERIODICALLY INSPECTED AND MONITORED. INCOMPATIBLE MATERIALS SHOULD BE ISOLATED FROM EACH OTHER.

3.45

Practically no odor

pK1 = 5.5; pK2 = 8.5

Hydrolyzes when diluted with water producing phosphoric acid.|On cooling it does not crystallize but sets to a rigid glass at -78 °C.|Little decomposition occurs up to 185 °C under vacuum but it cannot be distilled.|Anhydrous acid has no oxidizing character.|An aqueous solution shows the normal behavior of a dibasic acid; the first neutralization point is at pH 3.5 and the second at pH 8.5. Conductance measurements, however, indicate that it behaves as a monophasic acid in aqueous solution.

Soluble in water with release of heat.

Acids, Strong Non-oxidizing

Known Catalytic Activity

FLUOROPHOSPHORIC ACID neutralizes chemical bases (for example: amines and metal hydroxides) to form salts. Neutralization can generate dangerously large amounts of heat in small spaces. May react with active metals, including such structural metals as aluminum and iron, to release hydrogen, a flammable gas. Can initiate the polymerization of certain classes of organic compounds. Reacts with cyanide compounds to release gaseous hydrogen cyanide. May generate flammable and/or toxic gases in contact with dithiocarbamates, isocyanates, mercaptans, nitrides, nitriles, sulfides, and strong reducing agents. Incompatible with sodium tetrahydroborate. May react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), and carbonates. May catalyze (increase the rate) of chemical reactions.

Corrosive to glass since HF is present in the aqueous acid and can be generated by hydrolysis of the anhydrous acid.

II

8

UN 1776 8/PG 2

23/24/25-34

26-27-36/37/39-45

TE5000000

T,C

Corrosive

P261-P280-P301 + P310-P305 + P351 + P338-P310

H301 + H311 + H331-H314

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

INTERACTION OF SODIUM & OTHER TETRAHYDROBORATES WITH ANHYDROUS ACIDS (FLUOROPHOSPHORIC, PHOSPHORIC OR SULFURIC) TO GENERATE DIBORANE IS VERY EXOTHERMIC, & MAY BE DANGEROUSLY VIOLENT WITH RAPID MIXING.

MARTIN EE; DEVELOPMENT DOCUMENT FOR EFFLUENT LIMITATIONS GUIDELINES AND NEW SOURCE PERFORMANCE STANDARDS FOR PHOSPHORUS DERIVED CHEMICALS SEGMENT OF THE PHOSPHATE MANUFACTURING POINT SOURCE CATEGORY; US NTIS, PB REP: 158 PAGES (1974) ISS 241018. A STUDY WAS MADE OF THE PHOSPHATE MANUFACTURING POINT SOURCE CATEGORY FOR THE PURPOSE OF DEVELOPING EFFLUENT LIMITATIONS GUIDELINES, FEDERAL STANDARDS OF PERFORMANCE, AND PRETREATMENT STANDARDS FOR THE INDUSTRY. EFFLUENT LIMITATIONS GUIDELINES WERE DEVELOPED, DEFINING THE DEGREE OF EFFLUENT REDUCTION ATTAINABLE THROUGH THE APPLICATION OF THE BEST PRACTICABLE CONTROL TECHNOLOGY CURRENTLY AVAILABLE AND THE BEST AVAILABLE TECHNOLOGY ECONOMICALLY ACHIEVABLE. THE STANDARDS OF PERFORMANCE FOR NEW SOURCES WERE ALSO DEFINED. PROCESSES, WASTES, AND COSTS ARE ALSO DISCUSSED.|WHO; Diseases Caused by Phosphorus and Its Toxic Compounds; Early Detection of Occupational Diseases pg 53-62 (1986). Review of diseases and health related effects resulting from exposure to phosphorus or phosphorus cmpd.

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2016)|Corrosives, Reactive - 1st degree

|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P260, P264, P270, P271, P280, P284, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P320, P321, P322, P330, P361, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 43 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: SMALL FIRE: Dry chemical, CO2 or water spray. LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. Move containers from fire area if you can do it without risk. Dike fire-control water for later disposal; do not scatter the material. FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2016)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. (ERG, 2016)

THE BASIC VENTILATION METHODS ARE LOCAL EXHAUST VENTILATION AND DILUTION OR GENERAL VENTILATION.|SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.

/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Health: TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. /Fluorophosphoric acid, anhydrous/|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. /Fluorophosphoric acid, anhydrous/|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas. /Fluorophosphoric acid, anhydrous/|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. /Fluorophosphoric acid, anhydrous/|For more DOT Emergency Guidelines (Complete) data for MONOFLUOROPHOSPHORIC ACID (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Strong irritant to tissue.

DEXTRANASE INHIBITED FORMATION OF DENTAL PLAQUE & CARRIES IN RATS GIVEN A CARIOGENIC DIET AND INOCULATED WITH STREPTOCOCCUS MUTANS. THIS EFFECT WAS INCR BY ADDN OF MONOFLUOROPHOSPHATE TO THE WATER.

THE AMOUNT OF TOTAL FLUORIDE RETAINED AFTER BRUSHING WITH A DENTIFRICE WAS AN AVG 19.3% OF THAT APPLIED, WHILE THAT AFTER TOPICAL APPLICATION OF 2% NAF SOLN FOR 4 MIN WAS 13.6%. AFTER RINSING WITH 10 ML OF 500 PPM NAF SOLN FOR 30 SEC 11.6%, & AFTER CRUNCHING TABLET CONTAINING 1 MG F, 8.9% WAS RETAINED. AFTER MOUTH RINSING OR TOPICAL APPLICATION, RESIDUAL FLUORIDE WAS FOUND IN SALIVA FOR 24-48 HR. SALIVARY FLUORIDE WAS FOUND FOR ONLY 90-120 MIN AFTER APPLICATION OF MONOFLUOROPHOSPHATE CONTAINING DENTIFRICE OR FLUORIDE TABLETS.

HF, phosphoric acid, difluorophosphoric acid, hexafluorophosphoric acid (chemicals are in equilibrium with each other)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin. Keep victim calm and warm. Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed. (ERG, 2016)

Monitor plasma fluoride level because monofluorophosphoric acid may increase plasma fluoride levels and decrease plasma calcium.

STRONG IRRITANT TO TISSUE.|IN A DOUBLE-BLIND TRIAL WITH MONOFLUOROPHOSPHATE (25 MG FLUORIDE/DAY) GIVEN TO 460 AGED PERSONS (237 TREATED, 233 CONTROLS) FOR 8 MO, NO DIFFERENCE WAS OBSERVED IN HEIGHT, ADMISSION TO HOSPITAL, OR MORTALITY. FRACTURES AND EXACERBATION OF ARTHROSIS WERE MORE FREQUENT IN THE FLUORIDE GROUP. VERTEBRAL X-RAY FILMS SHOWED NO DIFFERENCE. THE FREE IONIZED FLUORIDE LEVELS IN THE PLASMA OF THE FLUORIDE-TREATED GROUP WERE STILL TWICE AS HIGH 2 MO AFTER TREATMENT ENDED.|SEE FLUORIDES. INORG FLUORIDES ARE GENERALLY HIGHLY IRRITANT AND TOXIC. ACUTE EFFECTS RESULTING FROM EXPOSURE TO FLUORINE COMPOUNDS ARE DUE TO HYDROGEN FLUORIDE. /FLUORIDES/

Fire Hazards -> Corrosives, Reactive - 1st degree