Pseudoginsenoside F11
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Pseudoginsenoside F11
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CAS No:
69884-00-0
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Formula:
C42H72O14
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Chemical Name:
Pseudoginsenoside F11
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Synonyms:
β-D-Glucopyranoside,(3β,6α,12β,24R)-20,24-epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-;Dammarane,β-D-glucopyranoside deriv.;(3β,6α,12β,24R)-20,24-Epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside;Pseudoginsenoside F11;Ginsenoside A1;67880-58-4
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CAS No:
Description
Pseudoginsenoside-F11 (PF11), a component of Panax quinquefolium (American ginseng), has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice. IC50 value: Inhibition of diprenorphine binding with an IC50 of 6.1 μM Target:In vitro: Biochemical experiments revealed that PF11 could inhibit diprenorphine (DIP) binding with an IC50 of 6.1 μM and reduced the binding potency of morphine in Chinese hamster ovary (CHO)-μ cel
Solid
Pseudoginsenoside F11 Use and Manufacturing
Ginsenoside F11 is one of the main components of American ginseng, which can resist the loss of learning and memory abilities induced by scopolamine, morphine and deoxyephedrine in mice.
Computed Properties
Molecular Weight:801.0
XLogP3:1.9
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:7
Exact Mass:800.49220697
Monoisotopic Mass:800.49220697
Topological Polar Surface Area:228
Heavy Atom Count:56
Complexity:1430
Undefined Atom Stereocenter Count:22
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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