Isoguanosine
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Isoguanosine
structure -
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CAS No:
1818-71-9
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Formula:
C10H13N5O5
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Chemical Name:
Isoguanosine
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Synonyms:
Adenosine,2,3-dihydro-2-oxo-;Isoguanosine;Adenosine,1,2-dihydro-2-oxo-;9H-Purin-2-ol,6-amino-9-Β-D-ribofuranosyl-;2,3-Dihydro-2-oxoadenosine;Crotonoside;9-β-D-Ribofuranosylisoguanine;Isoguanine riboside;2-Hydroxyadenosine;Crotonosid;NSC 12161;6-Amino-9[(1′-D-2′-ribofuranosyl)-4-hydroxy-5-(hydroxymethyl)-oxolan-2-yl]-1H-purin-2-one;484-79-7;27968-70-3
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CAS No:
Description
Crotonoside is isolated from Chinese medicinal herb, Croton. Crotonoside inhibits FLT3 and HDAC3/6, exhibits selective inhibition in acute myeloid leukemia (AML) cells. Crotonoside could be a promising new lead compound for the treatment of AML[1].
Characteristics
153
-3
2.25±0.1 g/cm3(Predicted)
237-241 °C @ Solvent: Water
831°C at 760 mmHg
456.4ºC
1.955
2.83E-29mmHg at 25°C
Computed Properties
Molecular Weight:283.24
XLogP3:-3
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:283.09166853
Monoisotopic Mass:283.09166853
Topological Polar Surface Area:153
Heavy Atom Count:20
Complexity:544
Undefined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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