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Isoguanosine

Isoguanosine structure

Isoguanosine 

structure
  • CAS No:

    1818-71-9

  • Formula:

    C10H13N5O5

  • Chemical Name:

    Isoguanosine

  • Synonyms:

    Adenosine,2,3-dihydro-2-oxo-;Isoguanosine;Adenosine,1,2-dihydro-2-oxo-;9H-Purin-2-ol,6-amino-9-Β-D-ribofuranosyl-;2,3-Dihydro-2-oxoadenosine;Crotonoside;9-β-D-Ribofuranosylisoguanine;Isoguanine riboside;2-Hydroxyadenosine;Crotonosid;NSC 12161;6-Amino-9[(1′-D-2′-ribofuranosyl)-4-hydroxy-5-(hydroxymethyl)-oxolan-2-yl]-1H-purin-2-one;484-79-7;27968-70-3

  • Categories:

    Biochemical Engineering  >  Plant Extracts

Description

Crotonoside is isolated from Chinese medicinal herb, Croton. Crotonoside inhibits FLT3 and HDAC3/6, exhibits selective inhibition in acute myeloid leukemia (AML) cells. Crotonoside could be a promising new lead compound for the treatment of AML[1].

Isoguanosine Basic Attributes

283.24

283.24

12161

29349990

Characteristics

153

-3

2.25±0.1 g/cm3(Predicted)

237-241 °C @ Solvent: Water

831°C at 760 mmHg

456.4ºC

1.955

2.83E-29mmHg at 25°C

Safety Information

NONH for all modes of transport

3

24/25

Drug Information

1,2-Dihydro-2-oxoadenosine

Computed Properties

Molecular Weight:283.24
XLogP3:-3
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:283.09166853
Monoisotopic Mass:283.09166853
Topological Polar Surface Area:153
Heavy Atom Count:20
Complexity:544
Undefined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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