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FMOC-ASP(ODMAB)-OH

FMOC-ASP(ODMAB)-OH structure

FMOC-ASP(ODMAB)-OH 

structure
  • CAS No:

    269066-08-2

  • Formula:

    C39H42N2O8

  • Chemical Name:

    FMOC-ASP(ODMAB)-OH

  • Synonyms:

    FMOC-L-ASPARTIC ACID BETA-4-[N-[1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEXYLIDENE)-3-METHYLBUTYL]AMINO]BENZYL ESTER;FMOC-ASP(ODMAB)-OH;FMOC-ASPARTIC ACID(ODMAB);N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-ASPARTIC ACID BETA-4-[N-[1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEXYLIDENE)-3-METHYLBUTYL]AMINO]BENZYL ESTER;N-ALPHA-FMOC-L-ASPARTIC ACID BETA-4-[N-[1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEXYLIDENE)-3-METHYLBUTYL]-AMINO] BENZYL ESTER;Fomc-Asp(Odmab)-OH;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartic acid 4-[[4-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]phenyl]methyl] ester;(S)-2-(((9H-fluoren-9-yl)methyl9H-fluoren-9-yl)methoxy)carbonylamino)-4-(4-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutylamino)benzyloxy)-4-oxobutanoic acid

  • Categories:

    Biochemical Engineering  >  Amino Acids and Derivatives

Description

Light yellow to off-white powder

FMOC-ASP(ODMAB)-OH Basic Attributes

666.76

666.294128

DTXSID70681027

Characteristics

148

7.04

1.3±0.1 g/cm3

841.0±65.0 °C at 760 mmHg

462.4±34.3 °C

1.608

-20°C

FMOC-ASP(ODMAB)-OH Use and Manufacturing

The Dmab group can be cleaved selectively in the presence of tBu-based protected groups by treatment with 2% hydrazine in DMF, making this derivative an extremely useful tool for the preparation of cyclic peptides by FMOC SPPS

Computed Properties

Molecular Weight:666.8
XLogP3:6.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:14
Exact Mass:666.29411630
Monoisotopic Mass:666.29411630
Topological Polar Surface Area:152
Heavy Atom Count:49
Complexity:1260
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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