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Home > Encyclopedia > N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine

N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine

N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine structure

N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine 

structure
  • CAS No:

    41088-86-2

  • Formula:

    C9H17NO5

  • Chemical Name:

    N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine

  • Synonyms:

    L-Homoserine,N-[(1,1-dimethylethoxy)carbonyl]-;N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine;N-tert-Butoxycarbonyl-L-homoserine;(S)-2-(tert-Butoxycarbonylamino)-4-hydroxybutanoic acid

  • Categories:

    Biochemical Engineering  >  Amino Acids and Derivatives

N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine Basic Attributes

219.23

219.24

2924199090

Characteristics

95.9

0.2

1.2±0.1 g/cm3

140°C(lit.)

421.6°C at 760 mmHg

208.8±27.3 °C

1.485

−20°C

Safety Information

NONH for all modes of transport

3

N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine Use and Manufacturing

Methods of Manufacturing

L-Homoserine (4.76 g, 40 mmol) and NaTo a solution of (S)-2-amino-4- hydroxybutanoic acid 205 (5 g, 41.6 mmol) in EtOH (50 mL) at room temperature was added TEA (4.2 g, 41.6 mmol) and B0C2O (9.1 g, 41.6 mmol). The resulting mixture was stirred at room temperature overnight. The crude mixture was concentrated to dryness to give crude title compound 206, (S)-2-(tert- butoxycarbonylamino)-4-hydroxybutanoic acid (8.5 g). LC-MS (LC method 1): m/z 220 (M+l)

Uses

Protected L-Homoserine (H615010).

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