N-[(1,1-Dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-L-serine
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N-[(1,1-Dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-L-serine
structure -
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CAS No:
13734-38-8
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Formula:
C12H23NO5
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Chemical Name:
N-[(1,1-Dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-L-serine
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Synonyms:
L-Serine,N-[(1,1-dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-;Alanine,3-tert-butoxy-N-carboxy-,N-tert-butyl ester,L-;N-[(1,1-Dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-L-serine;N-tert-Butoxycarbonyl-O-tert-butyl-L-serine;(2S)-3-tert-Butoxy-2-[(tert-butoxycarbonyl)amino]propanoic acid;NSC 334309;78: PN: WO2005023986 PAGE: 189 claimed protein;Boc-L-ser(OBu-t)-OH;(2S)-3-(tert-Butoxy)-2-[[(tert-butoxy)carbonyl]amino]propanoic acid;82594-36-3
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CAS No:
N-[(1,1-Dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-L-serine Basic Attributes
261.31
261.31
1533716-785-6
334309
2924199090
Characteristics
84.9
1.4
1.087±0.06 g/cm3(Predicted)
383.1±37.0 °C(Predicted)
185.5±26.5 °C
1.463
Store at 0°C
N-[(1,1-Dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-L-serine Use and Manufacturing
Compound (S)-3-(tert-butoxy)-2-((tert-butoxycarbonyl)amino)propanoic acid (10 g, 38.27 mmol), in a 500 mL single-necked flaskDimethylhydroxylamine hydrochloride (4.48 g, 45.92 mmol), 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (14.7 g, 76.68 mmol)And 4-dimethylaminopyridine (2.33g, 19mmol) dissolved in anhydrous dichloromethane (200mL), the reaction was stirred at room temperature until complete, Ethyl acetate and extracted with water, brine, dried, and concentrated to give the title compound 13a.
Computed Properties
Molecular Weight:261.31
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:261.15762283
Monoisotopic Mass:261.15762283
Topological Polar Surface Area:84.9
Heavy Atom Count:18
Complexity:301
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of N-[(1,1-Dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-L-serine
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Business licensed Certified factoryManufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances ChemicalsInquiryCAS No.: 13734-38-8Grade: Pharmaceutical GradeContent: 99% -
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N-[(1,1-Dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-L-serine
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