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ZM 323881 hydrochloride

ZM 323881 hydrochloride structure

CAS No:
193000-39-4
Formula:
C22H19ClFN3O2
Chemical Name:
ZM 323881 hydrochloride
Synonyms:
Phenol, 4-fluoro-2-methyl-5-[[7-(phenylmethoxy)-4-quinazolinyl]amino]-, hydrochloride (1:1);ZM 323881 HCl, >=99%
Categories:
Biochemical Engineering > Inhibitors

Description

ZM323881 hydrochloride is a potent and selective VEGFR2 inhibitor with an IC50 of less than 2 nM.

ZM 323881 hydrochloride is a hydrochloride obtained by combining ZM 323881 with one molar equivalent of hydrochloric acid. It has a role as a vascular endothelial growth factor receptor antagonist and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It contains a ZM 323881(1+).

ZM 323881 hydrochloride Basic Attributes

Molecular Weight：

411.8565632

Exact Mass：

411.114990

Characteristics

PSA：

67.27000

XLogP3：

5.98050

ZM 323881 hydrochloride Use and Manufacturing

Hydrochloride salt of ZM 323881, a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) with application towards cancer treatments.

Computed Properties

Molecular Weight:411.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:411.1149827
Monoisotopic Mass:411.1149827
Topological Polar Surface Area:67.3
Heavy Atom Count:29
Complexity:490
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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ZM323881HCL 99% see COA Kanbei kanbei

CAS No.: 193000-39-4

Grade: Industrial Grade

Content: 99%

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