NEUROKININ B
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NEUROKININ B
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CAS No:
86933-75-7
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Formula:
C55H79N13O14S2
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Chemical Name:
NEUROKININ B
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Synonyms:
NKB;NEUROMEDIN K;NEUROMEDIN K (HUMAN, PORCINE, BOVINE, RAT, MOUSE);NEUROKININ K;NEUROKININ BETA;NEUROKININ B (HUMAN, PORCINE);NEUROKININ B (HUMAN, PORCINE, BOVINE, RAT, MOUSE);NEUROKININ B
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Description
Neurokinin B belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs—including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect.
A mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family. It is similar in structure and action to SUBSTANCE P and NEUROKININ A with the ability to excite neurons, dilate blood vessels, and contract smooth muscles, such as those in the URINARY BLADDER and UTERUS.
Drug Information
Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. (See all compounds classified as Neurotransmitter Agents.)
Neurokinin B
Computed Properties
Molecular Weight:1210.4
XLogP3:-1.6
Hydrogen Bond Donor Count:14
Hydrogen Bond Acceptor Count:18
Rotatable Bond Count:38
Exact Mass:1209.53108659
Monoisotopic Mass:1209.53108659
Topological Polar Surface Area:485
Heavy Atom Count:84
Complexity:2220
Undefined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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