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Zeylenone

Zeylenone structure

Zeylenone 

structure
  • CAS No:

    193410-84-3

  • Formula:

    C21H18O7

  • Chemical Name:

    Zeylenone

  • Synonyms:

    2-Cyclohexen-1-one,4-(benzoyloxy)-6-[(benzoyloxy)methyl]-5,6-dihydroxy-,(4R,5S,6S)-;2-Cyclohexen-1-one,4-(benzoyloxy)-6-[(benzoyloxy)methyl]-5,6-dihydroxy-,[4R-(4α,5β,6β)]-;(4R,5S,6S)-4-(Benzoyloxy)-6-[(benzoyloxy)methyl]-5,6-dihydroxy-2-cyclohexen-1-one;Zeylenone;Tonkinenin A;(-)-Zeylenone;182219-68-7

  • Categories:

    Biochemical Engineering  >  Plant Extracts

Description

Zeylenone, isolated from ethanol extract of the leaves of Uvaria grandiflora Roxb. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways[1].

Zeylenone Basic Attributes

382.36342

382.36

DTXSID90441923

Characteristics

110.13000

3.78

1.41

150-152 °C

569.6±50.0 °C at 760 mmHg

201.4±23.6 °C

1.642

Drug Information

zeylenone

Computed Properties

Molecular Weight:382.4
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:382.10525291
Monoisotopic Mass:382.10525291
Topological Polar Surface Area:110
Heavy Atom Count:28
Complexity:616
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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