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Cucurbitacin E

Cucurbitacin E structure

Cucurbitacin E 

structure
  • CAS No:

    18444-66-1

  • Formula:

    C32H44O8

  • Chemical Name:

    Cucurbitacin E

  • Synonyms:

    19-Norlanosta-1,5,23-triene-3,11,22-trione,25-(acetyloxy)-2,16,20-trihydroxy-9-methyl-,(9β,10α,16α,23E)-;19-Nor-9β,10α-lanosta-1,5,23-triene-3,11,22-trione,2,16α,20,25-tetrahydroxy-9-methyl-,25-acetate;(9β,10α,16α,23E)-25-(Acetyloxy)-2,16,20-trihydroxy-9-methyl-19-norlanosta-1,5,23-triene-3,11,22-trione;Cucurbitacin E;α-Elaterin;Cucurbitacine E;α-Elaterine;NSC 106399;NSC 521775;32142-12-4;32142-32-8;32260-86-9

  • Categories:

    Biochemical Engineering  >  Chinese Herbs

Description

white to beige powderChEBI: A cucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at positions 1, 5 and 23.

Cucurbitacin E Basic Attributes

556.69

556.69

242-325-2

29153900

Characteristics

138

3.15

white to beige

1.1059 (rough estimate)

230 °C

545.56°C (rough estimate)

224.4±26.4 °C

1.4900 (estimate)

DMSO: soluble15mg/mL, clear

-20°C

1.84E-23mmHg at 25°C

Oral-Mouse LD50: 340 mg/kg; Abdominal cavity-mouse LD50: 2 mg/kg

Flammable, spicy and irritating smoke emitted from the fire

D -59° (c = 0.7 in chloroform)

Safety Information

3172

3

25-22

1-22-45-24/25

RC6305500

Xn

Treasury is low temperature, ventilated, dry; stored separately from food raw materials

P264, P270, P280, P301+P312, P302+P352, P312, P322, P330, P363, P501

H302

Toxicity

most toxic

Cucurbitacin E Use and Manufacturing

Cucurbitacin E is a biochemical compound from the family of Cucurbitacins. Cucurbitacin E is a highly oxidated steroid consisting of a tetracyclic triterpene. Cucurbitacin E is known to possess broad spectrum of potential anti-inflammatory, antitumor andantioxidant effects.

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