POLYPHYLLIN D
-
POLYPHYLLIN D
structure -
-
CAS No:
50773-41-6
-
Formula:
C44H70O16
-
Chemical Name:
POLYPHYLLIN D
-
Synonyms:
POLYPHYLLIN D;Polyphyllin;Polyphyllin I;Polyphyllin C;Paris saponin Pa;Polyphillin D;Polyphyllin A;Chonglou Saponin I(Polyphyllin A)
- Categories:
-
CAS No:
Description
Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis[1][2][3].
Drug Information
diosgenyl alpha-L-rhamnopyranosyl-(1-2)-(beta-L-ara-binofuranosyl-(1-4)-beta-D-glucopyranoside)
Computed Properties
Molecular Weight:855.0
XLogP3:1.5
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:16
Rotatable Bond Count:8
Exact Mass:854.46638614
Monoisotopic Mass:854.46638614
Topological Polar Surface Area:236
Heavy Atom Count:60
Complexity:1570
Defined Atom Stereocenter Count:25
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of POLYPHYLLIN D
-
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
CN
3 YRS
Business licensedTrader Supplier of Apigenin,PQQ,NMNHInquiryUnit Price: $10 /G EXWCAS No.: 50773-41-6Grade: Pharmaceutical gradeContent: 99% -
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 50773-41-6Grade: Industrial GradeContent: 99%
Learn More Other Chemicals
-
D 13223 (Flupirtine Metabolite)
95777-69-8
-
D 13223-d4 (Flupirtine Metabolite)
1216989-17-1
-
Streptothricin D sulfate
11076-96-3
-
Pulsatilla saponin D Formula
848784-85-0
-
BENZYL-D7 CYANIDE, 98 ATOM % D Formula
65538-26-3
-
Aspochalasin D Formula
71968-02-0
-
Bacillomycin D Structure
76012-17-4
-
ASCLEPOSIDE D Structure
325686-48-4
-
What is ASKENDOSIDE D
86408-17-5
-
What is Zaluzanin D
16838-85-0