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Home > Encyclopedia > Harpagoside

Harpagoside

Harpagoside structure

Harpagoside 

structure
  • CAS No:

    19210-12-9

  • Formula:

    C24H30O11

  • Chemical Name:

    Harpagoside

  • Synonyms:

    β-D-Glucopyranoside,(1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl;Harpagoside;β-D-Glucopyranoside,1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[(1-oxo-3-phenyl-2-propenyl)oxy]cyclopenta[c]pyran-1-yl,[1S-[1α,4aα,5α,7α(E),7aα]]-;β-D-Glucopyranoside,(1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propenyl]oxy]cyclopenta[c]pyran-1-yl;(1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-Hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl β-D-glucopyranoside;E-Harpagoside

  • Categories:

    Cosmetic Ingredient  >  Skin Conditioning

Description

Harpagoside is isolated from Harpagophytum procumbens (Hp). Harpagoside has inhibitory effects on COX-1 and COX-2 activity and inhibits NO production[1].


Harpagoside is a terpene glycoside.

Harpagoside Basic Attributes

494.49

494.49

242-881-6

8KGS1DC5ZU

29389090

Characteristics

175

-0.6

White to off-white powder.

1.52±0.1 g/cm3(Predicted)

120°C(dec.)

720.7±60.0 °C(Predicted)

244.3±26.4 °C

1.660

2-8°C

8.49E-22mmHg at 25°C

Safety Information

3172

3

22

22-45-24/25

Xn

P301 + P312 + P330

H302

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 42 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

Harpagophytum extract WS 1531

Harpagoside Use and Manufacturing

Uses

Standard for analysis of herbal products.

Lipids -> Prenol Lipids [PR] -> Isoprenoids [PR01] -> C10 isoprenoids (monoterpenes) [PR0102]

Computed Properties

Molecular Weight:494.5
XLogP3:-0.6
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:7
Exact Mass:494.17881177
Monoisotopic Mass:494.17881177
Topological Polar Surface Area:175
Heavy Atom Count:35
Complexity:811
Defined Atom Stereocenter Count:10
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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