Ethylene oxide-formaldehyde-4-(1,1,3,3-tetramethylbutyl)phenol copolymer
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Ethylene oxide-formaldehyde-4-(1,1,3,3-tetramethylbutyl)phenol copolymer
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CAS No:
25301-02-4
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Formula:
(C14H22O.C2H4O.CH2O)x
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Chemical Name:
Ethylene oxide-formaldehyde-4-(1,1,3,3-tetramethylbutyl)phenol copolymer
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Synonyms:
Formaldehyde,polymer with oxirane and 4-(1,1,3,3-tetramethylbutyl)phenol;Phenol,p-(1,1,3,3-tetramethylbutyl)-,polymer with ethylene oxide and formaldehyde;Ethylene oxide,polymer with formaldehyde and p-(1,1,3,3-tetramethylbutyl)phenol;Oxirane,polymer with formaldehyde and 4-(1,1,3,3-tetramethylbutyl)phenol;Phenol,4-(1,1,3,3-tetramethylbutyl)-,polymer with formaldehyde and oxirane;Triton WR 1339;Tyloxapol;Alevaire;Oxyethylated tertiary octyl-phenol-formaldehyde polymer;Superinone;Triton A 20;p-Isooctylpolyoxyethylenephenol formaldehyde polymer;Ethylene oxide-formaldehyde-p-octylphenol copolymer;NSC 90255;Ethylene oxide-formaldehyde-4-(1,1,3,3-tetramethylbutyl)phenol copolymer;9014-50-0;9015-10-5;9014-66-8
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CAS No:
Description
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surfactant to aid liquefaction.
Ethylene oxide-formaldehyde-4-(1,1,3,3-tetramethylbutyl)phenol copolymer Basic Attributes
137.17904
280.20384475 g/mol
DTXSID30179950
R - Respiratory system
29222990
Characteristics
49.83000
4.57360
Clear to hazy yellow to amber Viscous Liquid
1.1
282.3ºC at 760 mmHg
113 °C
Safety Information
NONH for all modes of transport
2
36/37/38
26-36
SM9750000
Xi
P305 + P351 + P338
H315-H319-H335
Drug Information
Purifying or cleansing agents, usually salts of long-chain aliphatic bases or acids, that exert cleansing (oil-dissolving) and antimicrobial effects through a surface action that depends on possessing both hydrophilic and hydrophobic properties. (See all compounds classified as Detergents.)|Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics. (See all compounds classified as Surface-Active Agents.)
Alevaire
Ethylene oxide-formaldehyde-4-(1,1,3,3-tetramethylbutyl)phenol copolymer Use and Manufacturing
anthelmintic, hepatotoxic
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:298.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:298.21440943
Monoisotopic Mass:298.21440943
Topological Polar Surface Area:77.8
Heavy Atom Count:21
Complexity:200
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Loxamic acid is a mast cell stabilizer. It inhibits type I rapid allergic reactions by inhibiting mast cell degranulation and reducing the permeability of target cell membranes to calcium ions, thereby preventing bronchospasm and decreased lung function caused by allergens. It can also inhibit the increase in skin vascular permeability caused by reagin, IgE and antigen-mediated reactions. When this drug is used for eye drops, it can produce the same reaction to the conjunctival vessels of the palpebral region and is used to treat allergic eye diseases. In vitro tests have confirmed that this drug prevents the release of histamine caused by specific antigens, and can also prevent the release of mast cells and other inflammatory mediators (such as SRS-A, i.e., the slow-reacting substance of allergic reactions, i.e., peptide-leukotrienes). Loxamic acid can also prevent the transfer of calcium ions into mast cells after stimulation, thereby inhibiting the release of histamine and inhibiting the chemotaxis of eosinophils. Generally, the therapeutic effect is obvious after 7 days of medication, and the symptoms can be controlled after 14-21 days of medication. If the treatment is continued, the condition will be further improved.
Registered Holders
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Curia (Beijing) Pharmaceutical Information Consulting Co., Ltd.
Active
China
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Jiangsu Poly Pharmaceutical Co., Ltd.
Active
China
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CURIA NEW YORK INC
Active
United States
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Ethylene oxide-formaldehyde-4-(1,1,3,3-tetramethylbutyl)phenol copolymer
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