Ethametsulfuron-methyl

Ethametsulfuron-methyl is a methyl ester resulting from the formal condensation of the carboxy group of ethametsulfuron with methanol. A herbicide used for the control of broad-leaved weeds in oil seed rape and fodder rape. It has a role as a herbicide and an EC 2.2.1.6 (acetolactate synthase) inhibitor. It is a diamino-1,3,5-triazine, a N-sulfonylurea, an aromatic ether, a benzoate ester and a methyl ester. It derives from an ethametsulfuron.

Preparation of 2-amino-4-methylamino-6-ethoxystriazine Dissolve 57g of cyanuric chloride in 800mL of acetone, cool to -10°C, pass 11g of ammonia, and react for 30min; add methylamine aqueous solution dropwise 84g, reacted at 30°C for 3h; after post-treatment, 46.5g of 2-amino-4-methylamino-6-chlorostriazine was obtained, melting point>230°C. Then it was refluxed with sodium ethoxide (10% CH3CH2ONa 224g) in ethanol solution (400mL) for 3h. After post-treatment, the product was 40.5g, m.p. 171.1-171.6℃, content>95%, yield 80%. For the preparation of methyl 2-formate benzenesulfonyl isocyanate, see the preparation method of metsulfuron-methyl. Synthesis of Tribensulfuron Dissolve 17.7 g of 2-amino-4-methylamino-6-ethoxy striazine in 6000 mL of dichloromethane, add 27.3 g of methyl phthalate benzenesulfonyl isocyanate dropwise, and react at room temperature After 3h, the solution gradually became milky white, stand still, filter, and dry to obtain triamsulfuron 35g, mp195℃, content>93%, yield>80%.

A broad-spectrum herbicide for rape fields, which can control broad-leaved weeds in rape fields and also has a significant inhibitory effect on grass weeds

Molecular Weight:410.4
XLogP3:1.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:8
Exact Mass:410.10085349
Monoisotopic Mass:410.10085349
Topological Polar Surface Area:170
Heavy Atom Count:28
Complexity:641
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes