Hypophyllanthin
-
Hypophyllanthin
structure -
-
CAS No:
33676-00-5
-
Formula:
C24H30O7
-
Chemical Name:
Hypophyllanthin
-
Synonyms:
Naphtho[1,2-d]-1,3-dioxole,9-(3,4-dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)-,(7S,8S,9R)-;Hypophyllanthin;Naphthalene,1α-(3,4-dimethoxyphenyl)-1,2,3,4-tetrahydro-6-methoxy-2β,3α-bis(methoxymethyl)-7,8-(methylenedioxy)-;Naphtho[1,2-d]-1,3-dioxole,9-(3,4-dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)-,(7α,8β,9α)-;Naphtho[1,2-d]-1,3-dioxole,9-(3,4-dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)-,(7R,8R,9S)-rel-;(7S,8S,9R)-9-(3,4-Dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)naphtho[1,2-d]-1,3-dioxole;NSC 619044
- Categories:
-
CAS No:
Description
Hypophyllanthin is a major lignan in Phyllanthus spp, with strong anti-inflammatory activity. Hypophyllanthin directly inhibits P-glycoprotein (P-gp) activity and did not interfere with multidrug resistance protein 2 (MRP2) activity[1][2].
Characteristics
64.61000
3.77
1.158
129-130 °C @ Solvent: Ethanol
511.1±50.0 °C at 760 mmHg
200.8±30.0 °C
1.536
Drug Information
(7R,8R,9S)-9-(3,4-dimethoxyphenyl)-4-methoxy-7,8-bis(methoxymethyl)-6,7,8,9-tetrahydronaphtho(1,2-d)(1,3)dioxole
Computed Properties
Molecular Weight:430.5
XLogP3:3.6
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:430.19915329
Monoisotopic Mass:430.19915329
Topological Polar Surface Area:64.6
Heavy Atom Count:31
Complexity:560
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of Hypophyllanthin
-
CN
3 YRS
Business licensedTrader Supplier of Apigenin,PQQ,NMNHInquiryUnit Price: $10 /G EXWCAS No.: 33676-00-5Grade: Pharmaceutical gradeContent: 99%
Learn More Other Chemicals
-
Nudol
86630-46-8
-
(1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bS)-10-acetyloxy-1,2,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,5,6,6a,7,8,8a,10,11,12,14b-tetradecahydropicene-4a-carboxylic acid
35959-01-4
-
Maritimetin
576-02-3
-
Isoscoparin Formula
20013-23-4
-
2,3-Dihydro-2,5-dihydroxy-6,8-dimethoxy-2-methyl-4H-naphtho[2,3-b]pyran-4-one Formula
1856-95-7
-
2,6-Di-tert-butyl-α-(dimethylamino)-p-cresol Formula
88-27-7
-
Agatharesinol Structure
7288-11-1
-
Niranthin Structure
50656-77-4
-
What is Sequirin C
18194-29-1
-
What is Hedyotisol B
95839-45-5