Ganodermanondiol
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Ganodermanondiol
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CAS No:
107900-76-5
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Formula:
C30H48O3
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Chemical Name:
Ganodermanondiol
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Synonyms:
Lanosta-7,9(11)-dien-3-one,24,25-dihydroxy-,(24S)-;(24S)-24,25-Dihydroxylanosta-7,9(11)-dien-3-one;Ganodermanondiol;(+)-Ganodermanondiol
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CAS No:
Description
Ganodermanondiol is a melanogenesis inhibitor isolated from the Ganoderma lucidum[1].Ganodermanondiol exhibits potent cytoprotective effects on tert-butyl hydroperoxide-induced hepatotoxicity[2]. Ganodermanondiol shows significant anti-HIV-1 protease activity with an IC50 of 90 μM[3]. Ganodermanondiol exhibits a strong anticomplement activity against the classical pathway of the complement system with an IC50 of 41.7μM[4].
Characteristics
57.53000
6.64
1.07±0.1 g/cm3(Predicted)
580.4±50.0 °C(Predicted)
318.9±26.6 °C
1.547
Computed Properties
Molecular Weight:456.7
XLogP3:5.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:456.36034539
Monoisotopic Mass:456.36034539
Topological Polar Surface Area:57.5
Heavy Atom Count:33
Complexity:879
Defined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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