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5,7-Dihydroxychromone

5,7-Dihydroxychromone structure

CAS No:
31721-94-5
Formula:
C9H6O4
Chemical Name:
5,7-Dihydroxychromone
Synonyms:
4H-1-Benzopyran-4-one,5,7-dihydroxy-;Chromone,5,7-dihydroxy-;5,7-Dihydroxy-4H-1-benzopyran-4-one;5,7-Dihydroxychromone;5,7-Dihydroxy-4-chromone
Categories:
Natural Products > Phenols

Description

5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1].

Solid

5,7-Dihydroxychromone is a member of chromones.

5,7-Dihydroxychromone Basic Attributes

Molecular Weight：

178.143

Exact Mass：

178.14

DSSTox ID：

DTXSID30185617

HScode：

2914400090

Characteristics

PSA：

66.8

XLogP3：

0.54

Density：

1.6±0.1 g/cm3

Melting Point：

272-273 °C

Boiling Point：

399℃

Flash Point：

171℃

Refractive Index：

1.689

Water Solubility：

9932 mg/L @ 25 °C (est)

Drug Information

MeSH Entry Terms：

5,7-dihydroxychromone

Computed Properties

Molecular Weight:178.14
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Exact Mass:178.02660867
Monoisotopic Mass:178.02660867
Topological Polar Surface Area:66.8
Heavy Atom Count:13
Complexity:248
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes