Ponasterone A

Ponasterone A is a 2beta-hydroxy steroid, a 3beta-hydroxy steroid, a 14alpha-hydroxy steroid, a 20-hydroxy steroid, a 22-hydroxy steroid, a 6-oxo steroid and a phytoecdysteroid.

Ponasterone A is a steroid compound of ecdysone, which is widely distributed in nature, and people have been extremely interested in it very long ago. As early as 1919, biologist Polish proposed the mechanism of insect ecdysone. In 1954, Butenadt and Kalson separated α-ecdysone from the silkworm pupa. In 1966, Nakanishi, Horm and other insect plants were used to extract Pannasterone. Later, many countries at home and abroad successively proposed ecdysone from many materials. Ecdysone can promote the synthesis of nucleic acids and proteins, affect the metabolism of sugar, promote lipid metabolism, immune regulation, affect the central nervous system, treat rheumatism, arthritis, anti-oxidative stress, anti-tumor effect. The performance of Ponasterone in certain neurosensing systems is 3-100 times that of β-ecdysone (β-ecdysone).

Molecular Weight:464.6
XLogP3:1.9
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:464.31378912
Monoisotopic Mass:464.31378912
Topological Polar Surface Area:118
Heavy Atom Count:33
Complexity:823
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes