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N,N′-Bis(trimethylsilyl)urea

N,N′-Bis(trimethylsilyl)urea structure

CAS No:
18297-63-7
Formula:
C7H20N2OSi2
Chemical Name:
N,N′-Bis(trimethylsilyl)urea
Synonyms:
Urea,N,N′-bis(trimethylsilyl)-;Urea,1,3-bis(trimethylsilyl)-;N,N′-Bis(trimethylsilyl)urea;N1,N2-Bis(trimethylsilyl)urea;1,3-Bis(trimethylsilyl)urea;Bis(trimethylsilyl)urea;TSL 8845;127290-39-5
Categories:
Chemical Reagents > Silane Reagent

Description

White solid with mild odorSilazane is any hydride of silicon and nitrogen having a straight or branched chain of silicon and nitrogen atoms joined by covalent bonds. By extension, the word is also used for any organic derivative of such compounds. They are analogous to siloxanes, with -NH- replacing -O-. Their individual name is dependent on the number of silicon atoms in the chemical structure.1,3-Bis(trimethylsilyl)urea is an effective silylating agent. It is used in the pharmaceutical

N,N′-Bis(trimethylsilyl)urea Basic Attributes

Molecular Weight：

204.42

Exact Mass：

204.42

BRN：

1937452

EC Number：

242-177-9

DSSTox ID：

DTXSID7066358

HScode：

29310095

Characteristics

PSA：

41.1

XLogP3：

1.76

Appearance：

White needle, crystalline powder with slight amine smell.

Density：

0.887

Melting Point：

222-224 °C

Boiling Point：

222°C

Flash Point：

65°C

Refractive Index：

1.427

Water Solubility：

Reacts with water.pyridine: soluble 100mg/mL, clear to slightly hazy, colorless to light yellow

Storage Conditions：

2-8°C

Vapor Pressure：

0.177mmHg at 25°C

Safety Information

Transport codes：

UN 1325 4.1/PG 2

wgk germany：

hazard class code：

11-36/37/38-20/21/22

safety instructions：

14-16-24/25-36-26

Marks：

F,Xn

Stability/Shelf Life：

Stable under normal temperatures and pressures.

Precautionary statement(s)：

P210

Hazard Statements：

H228

GHS Classification：

|Warning|H228 (91.11%): Flammable solid [Danger Flammable solids]|P210, P240, P241, P280, and P370+P378|Aggregated GHS information provided by 45 companies from 4 notifications to the ECHA C&L Inventory.

N,N′-Bis(trimethylsilyl)urea Use and Manufacturing

Uses

It is an excellent silylation reagent, which can replace the active hydrogen atoms in organic molecules with trimethyl silicon atom groups. This product is the most ideal silanization protective agent in the synthesis of β-lactam antibiotics. Silanization reagents can be used in the production of Ceflanka (Cefal IV) and Cefal VI.

Manufacturing Info：

Urea, N,N'-bis(trimethylsilyl)-: ACTIVE

Computed Properties

Molecular Weight:204.42
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:204.11141633
Monoisotopic Mass:204.11141633
Topological Polar Surface Area:41.1
Heavy Atom Count:12
Complexity:151
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of N,N′-Bis(trimethylsilyl)urea

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

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1,3-Bis(trimethylsilyl)urea

CAS No.: 18297-63-7

Content: 99.00%

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CAS No.: 18297-63-7

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Guide of N,N′-Bis(trimethylsilyl)urea

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
Learn More Other Chemicals

N,N′-Bis(trimethylsilyl)urea

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