Tinoridine hydrochloride
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Tinoridine hydrochloride
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CAS No:
25913-34-2
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Formula:
C17H20N2O2S.ClH
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Chemical Name:
Tinoridine hydrochloride
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Synonyms:
Thieno[2,3-c]pyridine-3-carboxylic acid,2-amino-4,5,6,7-tetrahydro-6-(phenylmethyl)-,ethyl ester,hydrochloride (1:1);Thieno[2,3-c]pyridine-3-carboxylic acid,2-amino-6-benzyl-4,5,6,7-tetrahydro-,ethyl ester,monohydrochloride;Thieno[2,3-c]pyridine-3-carboxylic acid,2-amino-4,5,6,7-tetrahydro-6-(phenylmethyl)-,ethyl ester,monohydrochloride;Y-3642 HCl;2-Amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine hydrochloride;Tinoridine hydrochloride
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CAS No:
Description
Tinoridine hydrochloride is a nonsteroidal anti-inflammatory drug and also has potent radical scavenger and antiperoxidative activity.
Tinoridine hydrochloride is a thienopyridine.
Characteristics
83.8
4.38640
1.256g/cm3
234-235 °C (decomp)
493.5ºC at 760mmHg
252.3ºC
7E-10mmHg at 25°C
Oral-rat LD50: 1200 mg/kg;Oral-Mouse LD50:1601 mg/kg
Flammable; burning produces fumes of toxic nitrogen oxides, sulfur oxides and hydrogen chloride
Drug Information
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
2-amino-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)-pyridine-3-carboxylic acid ethyl ester
Computed Properties
Molecular Weight:352.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:352.1012268
Monoisotopic Mass:352.1012268
Topological Polar Surface Area:83.8
Heavy Atom Count:23
Complexity:387
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
The pharmacological effects extracted from the above information are not clearly described.
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