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Cloperastine hydrochloride

Cloperastine hydrochloride structure

CAS No:
14984-68-0
Formula:
C20H24ClNO.ClH
Chemical Name:
Cloperastine hydrochloride
Synonyms:
Piperidine,1-[2-[(4-chlorophenyl)phenylmethoxy]ethyl]-,hydrochloride (1:1);Piperidine,1-[2-[(p-chloro-α-phenylbenzyl)oxy]ethyl]-,hydrochloride;Piperidine,1-[2-[(4-chlorophenyl)phenylmethoxy]ethyl]-,hydrochloride;p-Chlorobenzhydryl 2-(1-piperidyl)ethyl ether hydrochloride;HT 11;Hustazol;Cloperastine hydrochloride;Seki;Nitossil;Novotusil
Categories:
Active Pharmaceutical Ingredients > Antiallergic Drugs

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Description

Cloperastine hydrochloride is a diarylmethane.

Cloperastine hydrochloride Basic Attributes

Molecular Weight：

366.32

Exact Mass：

365.131317

EC Number：

239-067-8

NSC Number：

758635

DSSTox ID：

DTXSID5045413

HScode：

2933399090

Characteristics

PSA：

12.5

XLogP3：

5.67180

Melting Point：

147.9 °C

Boiling Point：

423.9ºC at 760 mmHg

Flash Point：

210.2ºC

Refractive Index：

1.414

Vapor Pressure：

2.15E-07mmHg at 25°C

Collision Cross Section：

180.4 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

RTECS Number：

TM6491500

Marks：

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 41 companies from 3 notifications to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

1-(2-((4-chloro-alpha-phenylbenzyl)oxy)ethyl)piperidine

Cloperastine hydrochloride Use and Manufacturing

Antitussive;'Histamine antagonist

Computed Properties

Molecular Weight:366.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:365.1313198
Monoisotopic Mass:365.1313198
Topological Polar Surface Area:12.5
Heavy Atom Count:24
Complexity:318
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Drug Function and Efficacy

This product is an analogue of diphenhydramine, which mainly suppresses cough center and relieves cough. It also has a weak antihistamine effect and has no dependence or tolerance. It takes effect 20-30 minutes after taking it and the effect lasts for 3-4 hours.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Cloperidin Hydrochloride Tablets
Ingredients	The content of cloperidine hydrochloride (C20H24ClNOHCl) in this product should be 90.0-110.0% of the labeled amount.
Indication	1. When used with central nervous system sedatives, it can increase drowsiness. 2. If used with other drugs at the same time, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	10mg
Manufacturer	Shanxi Zhendong Anxin Biopharmaceutical Co., Ltd.

Cloperidin Hydrochloride Tablets
Ingredients	The content of cloperidine hydrochloride (C20H24ClNOHCl) in this product should be 90.0-110.0% of the labeled amount.
Indication	1. When used with central nervous system sedatives, it can increase drowsiness. 2. If used with other drugs at the same time, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	10mg

Cloperidin Hydrochloride Tablets
Ingredients	The content of cloperidine hydrochloride (C20H24ClNOHCl) in this product should be 90.0-110.0% of the labeled amount.
Indication	1. When used with central nervous system sedatives, it can increase drowsiness. 2. If used with other drugs at the same time, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	10mg
Manufacturer	Jia Mu Si Luling Sunflower Pharmaceutical Group Co., Ltd.

See More Related Drugs

Registered Holders

SMILAX LABORATORIES LIMITED

India
Active
China Resources Double-Crane Pharmaceutical Co., Ltd.

China
Active
Liaoyuan City Baikang Pharmaceutical Co., Ltd.

China
Active

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Recommended Suppliers of Cloperastine hydrochloride

Shandong Airuike Chemical Co., Ltd. Contact Supplier

CN
2 YRS

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Cloperastine hydrochloride14984-68-0

CAS No.: 14984-68-0

Grade: Pharmaceutical Grade

Content: 99%

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Guide of Cloperastine hydrochloride

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Latest News
Learn More Other Chemicals

Cloperastine hydrochloride

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